GO Annotations Graph

• Symbol: Vdac1
• Name: voltage-dependent anion channel 1
• ID: MGI:106919

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0097001	ceramide binding	ISO	J:164563
Molecular Function	GO:0015485	cholesterol binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0005253	monoatomic anion channel activity	ISO	J:155856
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0031210	phosphatidylcholine binding	ISO	J:164563
Molecular Function	GO:0015288	porin activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:224799
Molecular Function	GO:0005515	protein binding	IPI	J:184429
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:164563
Molecular Function	GO:0008308	voltage-gated monoatomic anion channel activity	ISO	J:155856
Molecular Function	GO:0008308	voltage-gated monoatomic anion channel activity	IDA	J:150318
Molecular Function	GO:0008308	voltage-gated monoatomic anion channel activity	ISO	J:164563
Molecular Function	GO:0008308	voltage-gated monoatomic anion channel activity	IBA	J:265628
Molecular Function	GO:0008308	voltage-gated monoatomic anion channel activity	ISO	J:330207
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:150318
Cellular Component	GO:0005743	mitochondrial inner membrane	ISS	J:137567
Cellular Component	GO:0005743	mitochondrial inner membrane	HDA	J:100953
Cellular Component	GO:0031966	mitochondrial membrane	ISO	J:164563
Cellular Component	GO:0042645	mitochondrial nucleoid	ISO	J:164563
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:164563
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:155856
Cellular Component	GO:0005741	mitochondrial outer membrane	IBA	J:265628
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:120125
Cellular Component	GO:0005741	mitochondrial outer membrane	ISS	J:137567
Cellular Component	GO:0005757	mitochondrial permeability transition pore complex	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:268046
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	IDA	J:164856
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	IDA	J:192731
Cellular Component	GO:0005739	mitochondrion	IDA	J:233904
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	IDA	J:120125
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0046930	pore complex	IEA	J:60000
Cellular Component	GO:0098839	postsynaptic density membrane	ISO	J:155856
Cellular Component	GO:0048787	presynaptic active zone membrane	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Biological Process	GO:0006086	acetyl-CoA biosynthetic process from pyruvate	ISO	J:330207
Biological Process	GO:0006915	apoptotic process	ISO	J:164563
Biological Process	GO:0001662	behavioral fear response	IMP	J:76838
Biological Process	GO:0007268	chemical synaptic transmission	IMP	J:76838
Biological Process	GO:0007612	learning	IMP	J:76838
Biological Process	GO:0006851	mitochondrial calcium ion transmembrane transport	ISO	J:155856
Biological Process	GO:0098656	monoatomic anion transmembrane transport	IEA	J:72247
Biological Process	GO:0006820	monoatomic anion transport	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0110099	negative regulation of calcium import into the mitochondrion	ISO	J:164563
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	IMP	J:224799
Biological Process	GO:0007270	neuron-neuron synaptic transmission	IMP	J:76838
Biological Process	GO:1905091	positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	ISO	J:164563
Biological Process	GO:1903146	regulation of autophagy of mitochondrion	IMP	J:224799
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247