GO Annotations Graph

• Symbol: Aff3
• Name: AF4/FMR2 family, member 3
• ID: MGI:106927

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IMP	J:219240
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:219240
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TAS	J:76005
Molecular Function	GO:0003690	double-stranded DNA binding	IDA	J:219240
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:30625
Cellular Component	GO:0032783	super elongation complex	IBA	J:265628
Biological Process	GO:0006351	DNA-templated transcription	TAS	J:76005
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	ISO	J:164563
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	IEP	J:141871
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:219240
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:219240
Biological Process	GO:0010468	regulation of gene expression	IBA	J:265628
Biological Process	GO:0034612	response to tumor necrosis factor	ISO	J:164563