GO Annotations Graph

• Symbol: Ppp3cb
• Name: protein phosphatase 3, catalytic subunit, beta isoform
• ID: MGI:107163

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	ISO	J:155856
Molecular Function	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	TAS	Reactome:R-MMU-2025936
Molecular Function	GO:0005516	calmodulin binding	ISO	J:155856
Molecular Function	GO:0005516	calmodulin binding	ISO	J:164563
Molecular Function	GO:0005516	calmodulin binding	IBA	J:265628
Molecular Function	GO:0033192	calmodulin-dependent protein phosphatase activity	ISO	J:164563
Molecular Function	GO:0033192	calmodulin-dependent protein phosphatase activity	IMP	J:180489
Molecular Function	GO:0033192	calmodulin-dependent protein phosphatase activity	IBA	J:265628
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0017018	myosin phosphatase activity	IEA	J:72245
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:200382
Molecular Function	GO:0005515	protein binding	IPI	J:190017
Molecular Function	GO:0005515	protein binding	IPI	J:319680
Molecular Function	GO:0005515	protein binding	IPI	J:282598
Molecular Function	GO:0046983	protein dimerization activity	ISO	J:164563
Molecular Function	GO:0030346	protein phosphatase 2B binding	ISO	J:164563
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	IDA	J:77729
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	IDA	J:75775
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Cellular Component	GO:0005955	calcineurin complex	NAS	J:320122
Cellular Component	GO:0005955	calcineurin complex	ISO	J:164563
Cellular Component	GO:0005955	calcineurin complex	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	NAS	J:319677
Cellular Component	GO:0005829	cytosol	NAS	J:320049
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-2025936
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9010668
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:164000
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:164000
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:164000
Cellular Component	GO:0005886	plasma membrane	IDA	J:180489
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0008287	protein serine/threonine phosphatase complex	NAS	J:320050
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0030315	T-tubule	IDA	J:149624
Cellular Component	GO:0030018	Z disc	IDA	J:149624
Biological Process	GO:0097720	calcineurin-mediated signaling	ISO	J:164563
Biological Process	GO:0097720	calcineurin-mediated signaling	IBA	J:265628
Biological Process	GO:0033173	calcineurin-NFAT signaling cascade	ISO	J:164563
Biological Process	GO:0017156	calcium-ion regulated exocytosis	IDA	J:180489
Biological Process	GO:0007507	heart development	IMP	J:75775
Biological Process	GO:0031987	locomotion involved in locomotory behavior	IMP	J:109586
Biological Process	GO:0001946	lymphangiogenesis	IGI	J:149252
Biological Process	GO:0001946	lymphangiogenesis	IGI	J:149252
Biological Process	GO:1905949	negative regulation of calcium ion import across plasma membrane	NAS	J:319981
Biological Process	GO:0023057	negative regulation of signaling	IMP	J:319680
Biological Process	GO:0001915	negative regulation of T cell mediated cytotoxicity	IMP	J:130898
Biological Process	GO:1901386	negative regulation of voltage-gated calcium channel activity	NAS	J:319981
Biological Process	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	NAS	J:320049
Biological Process	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	NAS	J:319999
Biological Process	GO:1905665	positive regulation of calcium ion import across plasma membrane	NAS	J:319981
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	ISO	J:155856
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	IMP	J:180489
Biological Process	GO:1905673	positive regulation of lysosome organization	ISO	J:164563
Biological Process	GO:1900182	positive regulation of protein localization to nucleus	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:1901387	positive regulation of voltage-gated calcium channel activity	NAS	J:319981
Biological Process	GO:0006470	protein dephosphorylation	ISO	J:164563
Biological Process	GO:0006470	protein dephosphorylation	ISO	J:155856
Biological Process	GO:0006470	protein dephosphorylation	IMP	J:180489
Biological Process	GO:0006470	protein dephosphorylation	IMP	J:77729
Biological Process	GO:0006468	protein phosphorylation	IMP	J:180489
Biological Process	GO:0010468	regulation of gene expression	IMP	J:130898
Biological Process	GO:0050796	regulation of insulin secretion	ISO	J:155856
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:164000
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IMP	J:164000
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:164000
Biological Process	GO:0034097	response to cytokine	IMP	J:130898
Biological Process	GO:0006950	response to stress	IMP	J:109586
Biological Process	GO:0048741	skeletal muscle fiber development	IMP	J:110822
Biological Process	GO:0030217	T cell differentiation	IMP	J:77729
Biological Process	GO:0043029	T cell homeostasis	IMP	J:130898
Biological Process	GO:0001913	T cell mediated cytotoxicity	IMP	J:130898