Aurkb GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Aurkb
aurora kinase B
MGI:107168

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0044022	histone H3S28 kinase activity	IDA	J:203428
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0019900	kinase binding	ISO	J:164563
Molecular Function	GO:0140678	molecular function inhibitor activity	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:203428
Molecular Function	GO:0004672	protein kinase activity	ISO	J:155856
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IDA	J:272927
Molecular Function	GO:0004674	protein serine/threonine kinase activity	TAS	Reactome:R-MMU-9023138
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0010369	chromocenter	IDA	J:147064
Cellular Component	GO:0005694	chromosome	IDA	J:240155
Cellular Component	GO:0032133	chromosome passenger complex	ISO	J:164563
Cellular Component	GO:0032133	chromosome passenger complex	IBA	J:265628
Cellular Component	GO:0032133	chromosome passenger complex	IDA	J:162081
Cellular Component	GO:0000775	chromosome, centromeric region	IDA	J:240155
Cellular Component	GO:0000775	chromosome, centromeric region	IDA	J:240155
Cellular Component	GO:0000775	chromosome, centromeric region	IDA	J:240155
Cellular Component	GO:0000779	condensed chromosome, centromeric region	ISO	J:164563
Cellular Component	GO:0000779	condensed chromosome, centromeric region	IDA	J:90544
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0000776	kinetochore	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	IBA	J:265628
Cellular Component	GO:0000776	kinetochore	ISO	J:191250
Cellular Component	GO:0015630	microtubule cytoskeleton	ISO	J:164563
Cellular Component	GO:0030496	midbody	ISO	J:155856
Cellular Component	GO:0030496	midbody	ISO	J:164563
Cellular Component	GO:0030496	midbody	IDA	J:46390
Cellular Component	GO:1990023	mitotic spindle midzone	IDA	J:90544
Cellular Component	GO:0097431	mitotic spindle pole	IDA	J:240155
Cellular Component	GO:0097431	mitotic spindle pole	ISO	J:191250
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9023138
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:90544
Cellular Component	GO:0005819	spindle	ISO	J:155856
Cellular Component	GO:0005876	spindle microtubule	IBA	J:265628
Cellular Component	GO:0051233	spindle midzone	IBA	J:265628
Cellular Component	GO:0031616	spindle pole centrosome	IBA	J:265628
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0044839	cell cycle G2/M phase transition	ISO	J:164563
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0034644	cellular response to UV	ISO	J:164563
Biological Process	GO:0036089	cleavage furrow formation	ISO	J:155856
Biological Process	GO:0036089	cleavage furrow formation	ISO	J:164563
Biological Process	GO:0000278	mitotic cell cycle	NAS	J:319980
Biological Process	GO:0000281	mitotic cytokinesis	NAS	J:319980
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	IEA	J:72247
Biological Process	GO:0051256	mitotic spindle midzone assembly	ISO	J:164563
Biological Process	GO:0051256	mitotic spindle midzone assembly	NAS	J:319980
Biological Process	GO:0007052	mitotic spindle organization	NAS	J:319980
Biological Process	GO:0007052	mitotic spindle organization	IBA	J:265628
Biological Process	GO:0002903	negative regulation of B cell apoptotic process	ISO	J:164563
Biological Process	GO:0045824	negative regulation of innate immune response	ISO	J:164563
Biological Process	GO:0032091	negative regulation of protein binding	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:1902425	positive regulation of attachment of mitotic spindle microtubules to kinetochore	NAS	J:319980
Biological Process	GO:0032467	positive regulation of cytokinesis	ISO	J:164563
Biological Process	GO:1905116	positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore	ISO	J:164563
Biological Process	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	NAS	J:319980
Biological Process	GO:1903490	positive regulation of mitotic cytokinesis	NAS	J:319980
Biological Process	GO:0062033	positive regulation of mitotic sister chromatid segregation	ISO	J:164563
Biological Process	GO:1901970	positive regulation of mitotic sister chromatid separation	NAS	J:319980
Biological Process	GO:0001934	positive regulation of protein phosphorylation	NAS	J:319980
Biological Process	GO:0051973	positive regulation of telomerase activity	ISO	J:164563
Biological Process	GO:1904355	positive regulation of telomere capping	ISO	J:164563
Biological Process	GO:0032212	positive regulation of telomere maintenance via telomerase	ISO	J:164563
Biological Process	GO:0043687	post-translational protein modification	IDA	J:203428
Biological Process	GO:0034501	protein localization to kinetochore	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	NAS	J:319980
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0032465	regulation of cytokinesis	IBA	J:265628
Biological Process	GO:0007051	spindle organization	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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