GO Annotations Graph

• Symbol: Ppp3r2
• Name: protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II)
• ID: MGI:107171

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity	IBA	J:265628
Molecular Function	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity	IMP	J:226539
Molecular Function	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity	ISS	J:2181
Molecular Function	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity	ISO	J:73065
Molecular Function	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity	IDA	J:226539
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0019902	phosphatase binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:309565
Cellular Component	GO:0005955	calcineurin complex	NAS	J:320122
Cellular Component	GO:0005955	calcineurin complex	IBA	J:265628
Cellular Component	GO:0005955	calcineurin complex	IDA	J:2181
Cellular Component	GO:0005955	calcineurin complex	IDA	J:226539
Cellular Component	GO:0005955	calcineurin complex	IGI	J:226539
Cellular Component	GO:0005829	cytosol	NAS	J:320049
Cellular Component	GO:0005829	cytosol	NAS	J:319677
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0008287	protein serine/threonine phosphatase complex	NAS	J:320050
Cellular Component	GO:0036126	sperm flagellum	IDA	J:226539
Cellular Component	GO:0097225	sperm midpiece	IDA	J:309565
Cellular Component	GO:0097226	sperm mitochondrial sheath	IDA	J:309565
Biological Process	GO:0097720	calcineurin-mediated signaling	IBA	J:265628
Biological Process	GO:1905949	negative regulation of calcium ion import across plasma membrane	NAS	J:319981
Biological Process	GO:1901386	negative regulation of voltage-gated calcium channel activity	NAS	J:319981
Biological Process	GO:0007341	penetration of zona pellucida	IMP	J:226539
Biological Process	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	NAS	J:319999
Biological Process	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	NAS	J:320049
Biological Process	GO:1905665	positive regulation of calcium ion import across plasma membrane	NAS	J:319981
Biological Process	GO:1901387	positive regulation of voltage-gated calcium channel activity	NAS	J:319981
Biological Process	GO:0006470	protein dephosphorylation	IBA	J:265628