Bcl6 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Bcl6
B cell leukemia/lymphoma 6
MGI:107187

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:91929
Molecular Function	GO:0003682	chromatin binding	ISO	J:73065
Molecular Function	GO:0003682	chromatin binding	IDA	J:84005
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:117088
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:77745
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:193867
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	IDA	J:214293
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:185377
Molecular Function	GO:0005515	protein binding	IPI	J:219069
Molecular Function	GO:0005515	protein binding	IPI	J:217685
Molecular Function	GO:0005515	protein binding	IPI	J:94162
Molecular Function	GO:0005515	protein binding	IPI	J:214293
Molecular Function	GO:0005515	protein binding	IPI	J:48309
Molecular Function	GO:0005515	protein binding	IPI	J:218799
Molecular Function	GO:0005515	protein binding	IPI	J:197487
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:57856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:95859
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:39815
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:77745
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:98563
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0001222	transcription corepressor binding	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:48309
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0005634	nucleus	IDA	J:214293
Cellular Component	GO:0042382	paraspeckles	ISO	J:164563
Cellular Component	GO:0005657	replication fork	ISO	J:164563
Biological Process	GO:0030036	actin cytoskeleton organization	IMP	J:98043
Biological Process	GO:0030183	B cell differentiation	IGI	J:87846
Biological Process	GO:0042100	B cell proliferation	IMP	J:40769
Biological Process	GO:0000902	cell morphogenesis	IGI	J:98043
Biological Process	GO:0000902	cell morphogenesis	IMP	J:98043
Biological Process	GO:0048870	cell motility	IMP	J:98043
Biological Process	GO:0008283	cell population proliferation	IMP	J:96601
Biological Process	GO:0007160	cell-matrix adhesion	IMP	J:98043
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0048821	erythrocyte development	IMP	J:105042
Biological Process	GO:0002467	germinal center formation	IMP	J:111535
Biological Process	GO:0002467	germinal center formation	IMP	J:40769
Biological Process	GO:0002467	germinal center formation	IMP	J:42667
Biological Process	GO:0002467	germinal center formation	IMP	J:39815
Biological Process	GO:0031507	heterochromatin formation	IGI	J:197487
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0006954	inflammatory response	IEA	J:60000
Biological Process	GO:0048289	isotype switching to IgE isotypes	IGI	J:57856
Biological Process	GO:0048289	isotype switching to IgE isotypes	IMP	J:57856
Biological Process	GO:0070661	leukocyte proliferation	IMP	J:96601
Biological Process	GO:0070661	leukocyte proliferation	IMP	J:95859
Biological Process	GO:0032762	mast cell cytokine production	IMP	J:99053
Biological Process	GO:0032762	mast cell cytokine production	IMP	J:99053
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:82037
Biological Process	GO:0043066	negative regulation of apoptotic process	IDA	J:52960
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:164563
Biological Process	GO:0001953	negative regulation of cell-matrix adhesion	IMP	J:98043
Biological Process	GO:2000773	negative regulation of cellular senescence	IMP	J:193867
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0048294	negative regulation of isotype switching to IgE isotypes	IGI	J:57856
Biological Process	GO:0048294	negative regulation of isotype switching to IgE isotypes	IMP	J:57856
Biological Process	GO:0070664	negative regulation of leukocyte proliferation	IMP	J:96601
Biological Process	GO:0070664	negative regulation of leukocyte proliferation	IMP	J:95859
Biological Process	GO:0032764	negative regulation of mast cell cytokine production	IMP	J:99053
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	IGI	J:197487
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	IGI	J:197487
Biological Process	GO:1900099	negative regulation of plasma cell differentiation	IMP	J:91929
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	IMP	J:98043
Biological Process	GO:0045629	negative regulation of T-helper 2 cell differentiation	IGI	J:81987
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:84005
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:117088
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:39815
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:57856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:98563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:197487
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:77745
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:96601
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:95859
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:91929
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:39815
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:48309
Biological Process	GO:0002829	negative regulation of type 2 immune response	IGI	J:56751
Biological Process	GO:0002317	plasma cell differentiation	IMP	J:91929
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0030890	positive regulation of B cell proliferation	IMP	J:40769
Biological Process	GO:0045666	positive regulation of neuron differentiation	IDA	J:197487
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	ISO	J:164563
Biological Process	GO:0008104	protein localization	IMP	J:98043
Biological Process	GO:0021859	pyramidal neuron differentiation	IDA	J:197487
Biological Process	GO:0042127	regulation of cell population proliferation	IBA	J:265628
Biological Process	GO:0001817	regulation of cytokine production	IBA	J:265628
Biological Process	GO:0043087	regulation of GTPase activity	IMP	J:98043
Biological Process	GO:0002682	regulation of immune system process	IBA	J:265628
Biological Process	GO:0050727	regulation of inflammatory response	IBA	J:265628
Biological Process	GO:0050727	regulation of inflammatory response	IMP	J:39815
Biological Process	GO:0043380	regulation of memory T cell differentiation	IMP	J:91924
Biological Process	GO:0042129	regulation of T cell proliferation	IMP	J:91924
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IGI	J:214293
Biological Process	GO:0007266	Rho protein signal transduction	IMP	J:98043
Biological Process	GO:0007266	Rho protein signal transduction	IGI	J:98043
Biological Process	GO:0007266	Rho protein signal transduction	IMP	J:98043
Biological Process	GO:0007283	spermatogenesis	IMP	J:82037
Biological Process	GO:0045064	T-helper 2 cell differentiation	IGI	J:81987
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:197487
Biological Process	GO:0042092	type 2 immune response	IBA	J:265628
Biological Process	GO:0042092	type 2 immune response	IMP	J:40769

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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