GO Annotations Graph

• Symbol: Gpr143
• Name: G protein-coupled receptor 143
• ID: MGI:107193

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035240	dopamine binding	ISO	J:164563
Molecular Function	GO:0035240	dopamine binding	IBA	J:265628
Molecular Function	GO:0004930	G protein-coupled receptor activity	ISO	J:164563
Molecular Function	GO:0072544	L-DOPA binding	ISO	J:164563
Molecular Function	GO:0072544	L-DOPA binding	IBA	J:265628
Molecular Function	GO:0035643	L-DOPA receptor activity	ISO	J:164563
Molecular Function	GO:0035643	L-DOPA receptor activity	IBA	J:265628
Molecular Function	GO:0072545	tyrosine binding	ISO	J:164563
Molecular Function	GO:0072545	tyrosine binding	IBA	J:265628
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0042470	melanosome	ISO	J:164563
Cellular Component	GO:0033162	melanosome membrane	ISO	J:164563
Cellular Component	GO:0033162	melanosome membrane	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0035584	calcium-mediated signaling using intracellular calcium source	ISO	J:164563
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0032400	melanosome localization	ISO	J:164563
Biological Process	GO:0032438	melanosome organization	ISO	J:164563
Biological Process	GO:0032438	melanosome organization	IBA	J:265628
Biological Process	GO:0032402	melanosome transport	ISO	J:164563
Biological Process	GO:0048015	phosphatidylinositol-mediated signaling	ISO	J:164563
Biological Process	GO:0050848	regulation of calcium-mediated signaling	ISO	J:164563
Biological Process	GO:0050848	regulation of calcium-mediated signaling	IBA	J:265628
Biological Process	GO:1903056	regulation of melanosome organization	IMP	J:140473
Biological Process	GO:1902908	regulation of melanosome transport	IMP	J:140473
Biological Process	GO:0007165	signal transduction	IEA	J:60000