GO Annotations Graph

• Symbol: Shroom2
• Name: shroom family member 2
• ID: MGI:107194

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IDA	J:114885
Molecular Function	GO:0051015	actin filament binding	IDA	J:114885
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0051015	actin filament binding	IDA	J:124995
Molecular Function	GO:0008013	beta-catenin binding	IDA	J:114885
Molecular Function	GO:0005515	protein binding	IPI	J:124995
Molecular Function	GO:0019904	protein domain specific binding	IPI	J:124995
Molecular Function	GO:0019904	protein domain specific binding	IPI	J:124995
Cellular Component	GO:0005912	adherens junction	IDA	J:114885
Cellular Component	GO:0005912	adherens junction	IBA	J:265628
Cellular Component	GO:0043296	apical junction complex	IBA	J:265628
Cellular Component	GO:0043296	apical junction complex	IDA	J:124995
Cellular Component	GO:0016324	apical plasma membrane	ISS	J:121600
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:114885
Cellular Component	GO:0016324	apical plasma membrane	IBA	J:265628
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:114885
Cellular Component	GO:0005938	cell cortex	IDA	J:124995
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	IDA	J:124995
Cellular Component	GO:0030864	cortical actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0030864	cortical actin cytoskeleton	IDA	J:114885
Cellular Component	GO:0005737	cytoplasm	IDA	J:124995
Cellular Component	GO:0005856	cytoskeleton	IDA	J:114885
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005874	microtubule	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	IDA	J:124995
Cellular Component	GO:0005886	plasma membrane	IDA	J:114885
Biological Process	GO:0007015	actin filament organization	IBA	J:265628
Biological Process	GO:0045176	apical protein localization	ISS	J:121600
Biological Process	GO:0007420	brain development	ISS	J:121600
Biological Process	GO:0043010	camera-type eye development	ISS	J:121600
Biological Process	GO:0048593	camera-type eye morphogenesis	ISS	J:121600
Biological Process	GO:0016477	cell migration	IMP	J:114885
Biological Process	GO:0045217	cell-cell junction maintenance	IDA	J:124995
Biological Process	GO:0043482	cellular pigment accumulation	ISS	J:121600
Biological Process	GO:0043583	ear development	ISS	J:121600
Biological Process	GO:0032401	establishment of melanosome localization	ISS	J:121600
Biological Process	GO:0008057	eye pigment granule organization	ISS	J:121600
Biological Process	GO:0002089	lens morphogenesis in camera-type eye	ISS	J:121600
Biological Process	GO:0032438	melanosome organization	IMP	J:121600
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0030835	negative regulation of actin filament depolymerization	IDA	J:124995