GO Annotations Graph

• Symbol: Inpp5d
• Name: inositol polyphosphate-5-phosphatase D
• ID: MGI:107357

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0052659	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity	IEA	J:72245
Molecular Function	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity	IEA	J:72245
Molecular Function	GO:0030487	inositol-4,5-bisphosphate 5-phosphatase activity	ISO	J:155856
Molecular Function	GO:0016791	phosphatase activity	IEA	J:72247
Molecular Function	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	IEA	J:72245
Molecular Function	GO:0005515	protein binding	IPI	J:161854
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0005515	protein binding	IPI	J:127946
Molecular Function	GO:0005515	protein binding	IPI	J:113910
Molecular Function	GO:0005515	protein binding	IPI	J:124243
Molecular Function	GO:0005515	protein binding	IPI	J:84951
Molecular Function	GO:0005515	protein binding	IPI	J:84951
Cellular Component	GO:0005884	actin filament	ISO	J:155856
Cellular Component	GO:0030863	cortical cytoskeleton	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9680646
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9682158
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9682182
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0008340	determination of adult lifespan	IMP	J:48193
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0016064	immunoglobulin mediated immune response	IMP	J:60916
Biological Process	GO:0035556	intracellular signal transduction	IMP	J:60916
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0050869	negative regulation of B cell activation	IMP	J:60916
Biological Process	GO:0030889	negative regulation of B cell proliferation	IMP	J:60916
Biological Process	GO:0045779	negative regulation of bone resorption	IBA	J:265628
Biological Process	GO:0045779	negative regulation of bone resorption	IMP	J:78771
Biological Process	GO:0030853	negative regulation of granulocyte differentiation	IMP	J:48193
Biological Process	GO:0050777	negative regulation of immune response	IMP	J:60916
Biological Process	GO:0032715	negative regulation of interleukin-6 production	IMP	J:78771
Biological Process	GO:0045656	negative regulation of monocyte differentiation	IMP	J:48193
Biological Process	GO:0045659	negative regulation of neutrophil differentiation	IBA	J:265628
Biological Process	GO:0045659	negative regulation of neutrophil differentiation	IMP	J:48193
Biological Process	GO:0045671	negative regulation of osteoclast differentiation	IMP	J:78771
Biological Process	GO:0009968	negative regulation of signal transduction	IBA	J:265628
Biological Process	GO:0009968	negative regulation of signal transduction	IMP	J:78771
Biological Process	GO:0009968	negative regulation of signal transduction	IMP	J:60916
Biological Process	GO:0009968	negative regulation of signal transduction	IMP	J:48193
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	IEA	J:72247
Biological Process	GO:0043065	positive regulation of apoptotic process	IMP	J:78771
Biological Process	GO:0045579	positive regulation of B cell differentiation	IBA	J:265628
Biological Process	GO:0045579	positive regulation of B cell differentiation	IMP	J:48193
Biological Process	GO:0045579	positive regulation of B cell differentiation	IMP	J:60916
Biological Process	GO:0045648	positive regulation of erythrocyte differentiation	IMP	J:48193
Biological Process	GO:0045621	positive regulation of lymphocyte differentiation	IMP	J:48193
Biological Process	GO:0050776	regulation of immune response	IBA	J:265628