GO Annotations Graph

• Symbol: Rtkn
• Name: rhotekin
• ID: MGI:107371

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005525	GTP binding	IEA	J:60000
Molecular Function	GO:0005095	GTPase inhibitor activity	ISO	J:164563
Molecular Function	GO:0005095	GTPase inhibitor activity	IDA	J:33389
Molecular Function	GO:0005095	GTPase inhibitor activity	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:159310
Molecular Function	GO:0005515	protein binding	IPI	J:167914
Molecular Function	GO:0005515	protein binding	IPI	J:187542
Molecular Function	GO:0005515	protein binding	IPI	J:134634
Molecular Function	GO:0005515	protein binding	IPI	J:200374
Molecular Function	GO:0031267	small GTPase binding	ISO	J:164563
Molecular Function	GO:0031267	small GTPase binding	IDA	J:33389
Molecular Function	GO:0031267	small GTPase binding	IDA	J:99758
Cellular Component	GO:0005826	actomyosin contractile ring	IBA	J:265628
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5666183
Biological Process	GO:0000915	actomyosin contractile ring assembly	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0000281	mitotic cytokinesis	IBA	J:265628
Biological Process	GO:0042981	regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0007266	Rho protein signal transduction	ISO	J:164563
Biological Process	GO:0032185	septin cytoskeleton organization	IEA	J:72247
Biological Process	GO:0031106	septin ring organization	IBA	J:265628
Biological Process	GO:0007165	signal transduction	ISO	J:164563