GO Annotations Graph

• Symbol: Dnajc3
• Name: DnaJ heat shock protein family (Hsp40) member C3
• ID: MGI:107373

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051787	misfolded protein binding	IDA	J:156044
Molecular Function	GO:0051787	misfolded protein binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:156044
Molecular Function	GO:0019901	protein kinase binding	IPI	J:218404
Molecular Function	GO:0019901	protein kinase binding	IDA	J:218404
Molecular Function	GO:0004860	protein kinase inhibitor activity	IDA	J:218404
Molecular Function	GO:0004860	protein kinase inhibitor activity	ISS	J:33042
Molecular Function	GO:0051087	protein-folding chaperone binding	IDA	J:115988
Molecular Function	GO:0051087	protein-folding chaperone binding	IPI	J:156044
Molecular Function	GO:0051087	protein-folding chaperone binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:33042
Cellular Component	GO:0005829	cytosol	IDA	J:218404
Cellular Component	GO:0005829	cytosol	TAS	J:156044
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:218404
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005788	endoplasmic reticulum lumen	IDA	J:156044
Cellular Component	GO:0005790	smooth endoplasmic reticulum	ISO	J:155856
Biological Process	GO:0070417	cellular response to cold	IDA	J:218404
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	IC	J:156044
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	ISO	J:164563
Biological Process	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	IDA	J:218404
Biological Process	GO:0006469	negative regulation of protein kinase activity	ISS	J:33042
Biological Process	GO:0036494	positive regulation of translation initiation in response to endoplasmic reticulum stress	IDA	J:218404
Biological Process	GO:0034975	protein folding in endoplasmic reticulum	IBA	J:265628
Biological Process	GO:0051603	proteolysis involved in protein catabolic process	IDA	J:156044
Biological Process	GO:0006417	regulation of translation	IEA	J:60000
Biological Process	GO:0034976	response to endoplasmic reticulum stress	IMP	J:115988
Biological Process	GO:0006986	response to unfolded protein	IEA	J:60000