GO Annotations Graph

• Symbol: Pitx1
• Name: paired-like homeodomain transcription factor 1
• ID: MGI:107374

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:33258
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:155856
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:41049
Molecular Function	GO:0005515	protein binding	IPI	J:41049
Molecular Function	GO:0005515	protein binding	IPI	J:41049
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:33258
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:150130
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:150130
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:41049
Biological Process	GO:0009653	anatomical structure morphogenesis	IBA	J:265628
Biological Process	GO:0014707	branchiomeric skeletal muscle development	IMP	J:120320
Biological Process	GO:0051216	cartilage development	IMP	J:52671
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	IMP	J:178677
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	IGI	J:131535
Biological Process	GO:0035137	hindlimb morphogenesis	IMP	J:53310
Biological Process	GO:0035137	hindlimb morphogenesis	IMP	J:52671
Biological Process	GO:0035137	hindlimb morphogenesis	IDA	J:114714
Biological Process	GO:0035137	hindlimb morphogenesis	IDA	J:95804
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0048625	myoblast fate commitment	IMP	J:120320
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:219080
Biological Process	GO:0021983	pituitary gland development	IMP	J:53310
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:33258
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:41049
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:41049
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:41049
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:56497
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:41049
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:41049
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:41049
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:41049
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:56497
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:56497
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0001501	skeletal system development	IMP	J:52671