GO Annotations Graph

• Symbol: Tbr1
• Name: T-box brain transcription factor 1
• ID: MGI:107404

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:266522
Molecular Function	GO:0003677	DNA binding	IDA	J:94801
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:90129
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:162313
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:90129
Cellular Component	GO:0005634	nucleus	IDA	J:105185
Biological Process	GO:0021764	amygdala development	IMP	J:208050
Biological Process	GO:0001708	cell fate specification	IBA	J:265628
Biological Process	GO:0021987	cerebral cortex development	IMP	J:266522
Biological Process	GO:0006338	chromatin remodeling	IMP	J:266522
Biological Process	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	IBA	J:265628
Biological Process	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	IGI	J:192361
Biological Process	GO:0001661	conditioned taste aversion	IMP	J:208050
Biological Process	GO:0010467	gene expression	IMP	J:266522
Biological Process	GO:0030902	hindbrain development	IMP	J:106708
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0030182	neuron differentiation	IMP	J:162313
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:94801
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:94801
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:94801
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:94801
Biological Process	GO:1902667	regulation of axon guidance	IMP	J:208050
Biological Process	GO:1902667	regulation of axon guidance	IMP	J:76341
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0010468	regulation of gene expression	IMP	J:162313
Biological Process	GO:0010975	regulation of neuron projection development	IBA	J:265628
Biological Process	GO:0010975	regulation of neuron projection development	IMP	J:162313
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0010092	specification of animal organ identity	IMP	J:162313