Gdnf GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Gdnf
glial cell line derived neurotrophic factor
MGI:107430

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030116	glial cell-derived neurotrophic factor receptor binding	ISO	J:155856
Molecular Function	GO:0008083	growth factor activity	ISO	J:155856
Molecular Function	GO:0008083	growth factor activity	IBA	J:265628
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:155856
Molecular Function	GO:0048018	receptor ligand activity	ISO	J:155856
Molecular Function	GO:0030971	receptor tyrosine kinase binding	ISO	J:155856
Molecular Function	GO:0005160	transforming growth factor beta receptor binding	TAS	J:54911
Cellular Component	GO:0005576	extracellular region	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0043235	receptor complex	ISO	J:155856
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IMP	J:33810
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IDA	J:85564
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IDA	J:171473
Biological Process	GO:0008283	cell population proliferation	ISO	J:155856
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	ISO	J:155856
Biological Process	GO:0071679	commissural neuron axon guidance	IGI	J:188327
Biological Process	GO:0021516	dorsal spinal cord development	IMP	J:188327
Biological Process	GO:0048568	embryonic organ development	IMP	J:188327
Biological Process	GO:0048484	enteric nervous system development	IMP	J:33809
Biological Process	GO:0048484	enteric nervous system development	IDA	J:33808
Biological Process	GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	IEP	J:54493
Biological Process	GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	ISO	J:155856
Biological Process	GO:0001656	metanephros development	IMP	J:33808
Biological Process	GO:0001656	metanephros development	IGI	J:122519
Biological Process	GO:0001656	metanephros development	IGI	J:90324
Biological Process	GO:0001656	metanephros development	IMP	J:122519
Biological Process	GO:0048255	mRNA stabilization	ISO	J:164563
Biological Process	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	ISO	J:164563
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	ISO	J:164563
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IBA	J:265628
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:95816
Biological Process	GO:0007399	nervous system development	IMP	J:33808
Biological Process	GO:0001755	neural crest cell migration	ISO	J:73065
Biological Process	GO:1901166	neural crest cell migration involved in autonomic nervous system development	ISO	J:229828
Biological Process	GO:0030182	neuron differentiation	ISO	J:155856
Biological Process	GO:0031175	neuron projection development	ISO	J:73065
Biological Process	GO:0001759	organ induction	IGI	J:96485
Biological Process	GO:0007422	peripheral nervous system development	IBA	J:265628
Biological Process	GO:0007422	peripheral nervous system development	IMP	J:95816
Biological Process	GO:0007422	peripheral nervous system development	IMP	J:73922
Biological Process	GO:0030432	peristalsis	IMP	J:33810
Biological Process	GO:0030432	peristalsis	IMP	J:73922
Biological Process	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	ISO	J:164563
Biological Process	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	ISO	J:155856
Biological Process	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	IMP	J:175174
Biological Process	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	IBA	J:265628
Biological Process	GO:0045597	positive regulation of cell differentiation	ISO	J:202649
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:202649
Biological Process	GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	IMP	J:33809
Biological Process	GO:0032770	positive regulation of monooxygenase activity	ISO	J:164563
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0072107	positive regulation of ureteric bud formation	ISO	J:164563
Biological Process	GO:0021784	postganglionic parasympathetic fiber development	IMP	J:33810
Biological Process	GO:0001941	postsynaptic membrane organization	IDA	J:93581
Biological Process	GO:0051584	regulation of dopamine uptake involved in synaptic transmission	ISO	J:164563
Biological Process	GO:0010468	regulation of gene expression	ISO	J:202649
Biological Process	GO:0060688	regulation of morphogenesis of a branching structure	IDA	J:85564
Biological Process	GO:2001260	regulation of semaphorin-plexin signaling pathway	IGI	J:188327
Biological Process	GO:0072106	regulation of ureteric bud formation	ISO	J:155856
Biological Process	GO:0009611	response to wounding	ISO	J:155856
Biological Process	GO:0048485	sympathetic nervous system development	IMP	J:33808
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	TAS	J:54911
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	TAS	J:72723
Biological Process	GO:0001657	ureteric bud development	IDA	J:99437
Biological Process	GO:0001657	ureteric bud development	IGI	J:96485
Biological Process	GO:0060676	ureteric bud formation	IMP	J:33810

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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