GO Annotations Graph

• Symbol: Efna5
• Name: ephrin A5
• ID: MGI:107444

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0045499	chemorepellent activity	IDA	J:99629
Molecular Function	GO:0046875	ephrin receptor binding	IPI	J:38350
Molecular Function	GO:0046875	ephrin receptor binding	ISO	J:155856
Molecular Function	GO:0046875	ephrin receptor binding	IPI	J:77779
Molecular Function	GO:0046875	ephrin receptor binding	ISO	J:164563
Molecular Function	GO:0046875	ephrin receptor binding	IBA	J:265628
Molecular Function	GO:0005169	neurotrophin TRKB receptor binding	IPI	J:184958
Molecular Function	GO:0005515	protein binding	IPI	J:184958
Molecular Function	GO:0005515	protein binding	IPI	J:51889
Cellular Component	GO:0005912	adherens junction	IDA	J:194293
Cellular Component	GO:0005604	basement membrane	IDA	J:194293
Cellular Component	GO:0071944	cell periphery	IDA	J:194293
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:164563
Cellular Component	GO:0098982	GABA-ergic synapse	IEP	J:204427
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:204427
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:204427
Cellular Component	GO:0098982	GABA-ergic synapse	IPI	J:204427
Cellular Component	GO:0098982	GABA-ergic synapse	IPI	J:204427
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IDA	J:177156
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0007411	axon guidance	IBA	J:265628
Biological Process	GO:0007411	axon guidance	IMP	J:67679
Biological Process	GO:0007411	axon guidance	IDA	J:47983
Biological Process	GO:0007420	brain development	ISO	J:155856
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0071372	cellular response to follicle-stimulating hormone stimulus	IDA	J:194293
Biological Process	GO:1904322	cellular response to forskolin	IDA	J:194293
Biological Process	GO:0048668	collateral sprouting	IDA	J:184958
Biological Process	GO:0048013	ephrin receptor signaling pathway	IDA	J:177156
Biological Process	GO:0048013	ephrin receptor signaling pathway	IDA	J:38350
Biological Process	GO:0048013	ephrin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0048013	ephrin receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	ISO	J:194293
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0048672	positive regulation of collateral sprouting	IMP	J:184958
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IDA	J:177156
Biological Process	GO:0051965	positive regulation of synapse assembly	IDA	J:184958
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	IDA	J:177156
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	IBA	J:265628
Biological Process	GO:0022604	regulation of cell morphogenesis	ISO	J:194293
Biological Process	GO:0022407	regulation of cell-cell adhesion	IDA	J:77779
Biological Process	GO:0022407	regulation of cell-cell adhesion	ISO	J:164563
Biological Process	GO:0022407	regulation of cell-cell adhesion	IBA	J:265628
Biological Process	GO:0051893	regulation of focal adhesion assembly	ISO	J:164563
Biological Process	GO:0043087	regulation of GTPase activity	IDA	J:177156
Biological Process	GO:0043087	regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	IMP	J:177156
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	ISO	J:164563
Biological Process	GO:0031290	retinal ganglion cell axon guidance	IDA	J:99629
Biological Process	GO:0099560	synaptic membrane adhesion	IEP	J:204427
Biological Process	GO:0099560	synaptic membrane adhesion	IDA	J:204427
Biological Process	GO:0099560	synaptic membrane adhesion	IPI	J:204427
Biological Process	GO:0099560	synaptic membrane adhesion	IPI	J:204427
Biological Process	GO:0099560	synaptic membrane adhesion	IMP	J:204427