GO Annotations Graph

• Symbol: Pex2
• Name: peroxisomal biogenesis factor 2
• ID: MGI:107486

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046872	metal ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ISO	J:164563
Cellular Component	GO:0016593	Cdc73/Paf1 complex	ISO	J:164563
Cellular Component	GO:0016593	Cdc73/Paf1 complex	IBA	J:265628
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005778	peroxisomal membrane	ISO	J:164563
Cellular Component	GO:0005778	peroxisomal membrane	ISO	J:155856
Cellular Component	GO:0005777	peroxisome	ISO	J:155856
Biological Process	GO:0006699	bile acid biosynthetic process	IMP	J:87591
Biological Process	GO:0034614	cellular response to reactive oxygen species	ISO	J:164563
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:87591
Biological Process	GO:0006635	fatty acid beta-oxidation	ISO	J:164563
Biological Process	GO:0006635	fatty acid beta-oxidation	IBA	J:265628
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	ISO	J:164563
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IMP	J:83644
Biological Process	GO:0001764	neuron migration	IMP	J:83644
Biological Process	GO:0007031	peroxisome organization	ISO	J:164563
Biological Process	GO:0007031	peroxisome organization	IMP	J:44975
Biological Process	GO:0007031	peroxisome organization	IBA	J:265628
Biological Process	GO:0000425	pexophagy	ISO	J:164563
Biological Process	GO:0031648	protein destabilization	ISO	J:164563
Biological Process	GO:0016558	protein import into peroxisome matrix	ISO	J:164563
Biological Process	GO:0016562	protein import into peroxisome matrix, receptor recycling	ISO	J:164563
Biological Process	GO:0006513	protein monoubiquitination	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0045540	regulation of cholesterol biosynthetic process	IMP	J:87591
Biological Process	GO:1990928	response to amino acid starvation	ISO	J:164563
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	ISO	J:164563
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	IBA	J:265628