GO Annotations Graph

• Symbol: Pdcd4
• Name: programmed cell death 4
• ID: MGI:107490

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:145850
Molecular Function	GO:0005515	protein binding	IPI	J:113966
Molecular Function	GO:0005515	protein binding	IPI	J:114111
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0030509	BMP signaling pathway	ISO	J:164563
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IMP	J:158464
Biological Process	GO:0060940	epithelial to mesenchymal transition involved in cardiac fibroblast development	ISO	J:155856
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:1900016	negative regulation of cytokine production involved in inflammatory response	IMP	J:158464
Biological Process	GO:1900016	negative regulation of cytokine production involved in inflammatory response	IMP	J:120583
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:1904761	negative regulation of myofibroblast differentiation	ISO	J:164563
Biological Process	GO:1905064	negative regulation of vascular associated smooth muscle cell differentiation	ISO	J:164563
Biological Process	GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	ISO	J:164563
Biological Process	GO:2000353	positive regulation of endothelial cell apoptotic process	ISO	J:164563
Biological Process	GO:0050729	positive regulation of inflammatory response	IMP	J:158464
Biological Process	GO:0050729	positive regulation of inflammatory response	IMP	J:120583
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0034393	positive regulation of smooth muscle cell apoptotic process	ISO	J:155856
Biological Process	GO:1905461	positive regulation of vascular associated smooth muscle cell apoptotic process	ISO	J:164563
Biological Process	GO:0051246	regulation of protein metabolic process	ISO	J:155856