GO Annotations Graph

• Symbol: Kcnj11
• Name: potassium inwardly rectifying channel, subfamily J, member 11
• ID: MGI:107501

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030506	ankyrin binding	ISO	J:164563
Molecular Function	GO:0030506	ankyrin binding	IPI	J:166301
Molecular Function	GO:0030506	ankyrin binding	ISO	J:155856
Molecular Function	GO:0005524	ATP binding	IDA	J:135491
Molecular Function	GO:0015272	ATP-activated inward rectifier potassium channel activity	IDA	J:135498
Molecular Function	GO:0015272	ATP-activated inward rectifier potassium channel activity	ISO	J:155856
Molecular Function	GO:0015272	ATP-activated inward rectifier potassium channel activity	IBA	J:265628
Molecular Function	GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0019855	calcium channel inhibitor activity	IMP	J:311843
Molecular Function	GO:0019855	calcium channel inhibitor activity	IDA	J:34708
Molecular Function	GO:0019855	calcium channel inhibitor activity	IMP	J:144673
Molecular Function	GO:0019855	calcium channel inhibitor activity	IDA	J:34708
Molecular Function	GO:0019855	calcium channel inhibitor activity	IMP	J:311843
Molecular Function	GO:0031072	heat shock protein binding	ISO	J:155856
Molecular Function	GO:0005242	inward rectifier potassium channel activity	IMP	J:144673
Molecular Function	GO:0005242	inward rectifier potassium channel activity	IMP	J:311843
Molecular Function	GO:0005242	inward rectifier potassium channel activity	IDA	J:34708
Molecular Function	GO:0005242	inward rectifier potassium channel activity	IDA	J:34708
Molecular Function	GO:0005242	inward rectifier potassium channel activity	IMP	J:311843
Molecular Function	GO:0030955	potassium ion binding	IC	J:135498
Molecular Function	GO:0005515	protein binding	IPI	J:224748
Molecular Function	GO:0005515	protein binding	IPI	J:153221
Molecular Function	GO:0005515	protein binding	IPI	J:200432
Molecular Function	GO:0005515	protein binding	IPI	J:166301
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:164563
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Molecular Function	GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	ISO	J:164563
Molecular Function	GO:0005249	voltage-gated potassium channel activity	ISO	J:164563
Cellular Component	GO:0001669	acrosomal vesicle	ISO	J:155856
Cellular Component	GO:0030673	axolemma	ISO	J:155856
Cellular Component	GO:0070852	cell body fiber	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0005768	endosome	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0014704	intercalated disc	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0008282	inward rectifying potassium channel	ISO	J:164563
Cellular Component	GO:0008282	inward rectifying potassium channel	ISO	J:155856
Cellular Component	GO:0008282	inward rectifying potassium channel	IDA	J:135498
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0043209	myelin sheath	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005635	nuclear envelope	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:144673
Cellular Component	GO:0005886	plasma membrane	IDA	J:34708
Cellular Component	GO:0005886	plasma membrane	IDA	J:103335
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0042383	sarcolemma	ISO	J:155856
Cellular Component	GO:0030315	T-tubule	ISO	J:155856
Cellular Component	GO:0030315	T-tubule	IDA	J:166301
Biological Process	GO:0006006	glucose metabolic process	ISO	J:164563
Biological Process	GO:0098662	inorganic cation transmembrane transport	ISO	J:155856
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0046676	negative regulation of insulin secretion	ISO	J:164563
Biological Process	GO:0046676	negative regulation of insulin secretion	IMP	J:144673
Biological Process	GO:0046676	negative regulation of insulin secretion	IMP	J:311843
Biological Process	GO:0050877	nervous system process	ISO	J:164563
Biological Process	GO:2001259	positive regulation of cation channel activity	ISO	J:155856
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	ISO	J:155856
Biological Process	GO:1990573	potassium ion import across plasma membrane	ISO	J:155856
Biological Process	GO:1990573	potassium ion import across plasma membrane	IDA	J:135498
Biological Process	GO:1990573	potassium ion import across plasma membrane	IBA	J:265628
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0006813	potassium ion transport	ISO	J:155856
Biological Process	GO:0050796	regulation of insulin secretion	ISO	J:164563
Biological Process	GO:0042391	regulation of membrane potential	ISO	J:164563
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IBA	J:265628
Biological Process	GO:0033198	response to ATP	ISO	J:164563
Biological Process	GO:0033198	response to ATP	ISO	J:155856
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:164563