GO Annotations Graph

• Symbol: Cln3
• Name: CLN3 lysosomal/endosomal transmembrane protein, battenin
• ID: MGI:107537

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0048306	calcium-dependent protein binding	IPI	J:117797
Molecular Function	GO:0051861	glycolipid binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:235261
Molecular Function	GO:0005515	protein binding	IPI	J:117797
Molecular Function	GO:0120146	sulfatide binding	ISO	J:164563
Cellular Component	GO:0044754	autolysosome	IDA	J:114863
Cellular Component	GO:0005776	autophagosome	IDA	J:114863
Cellular Component	GO:0005901	caveola	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	IDA	J:117797
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0005769	early endosome	IDA	J:95873
Cellular Component	GO:0031901	early endosome membrane	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0005768	endosome	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0000139	Golgi membrane	ISO	J:164563
Cellular Component	GO:0005795	Golgi stack	ISO	J:164563
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0005770	late endosome	IDA	J:95873
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IDA	J:282692
Cellular Component	GO:0005764	lysosome	IDA	J:235261
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IBA	J:265628
Cellular Component	GO:0005764	lysosome	IDA	J:95873
Cellular Component	GO:0005764	lysosome	IDA	J:114863
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0045121	membrane raft	IDA	J:204172
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	IDA	J:282692
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0055037	recycling endosome	ISO	J:164563
Cellular Component	GO:0045202	synapse	IEA	J:60000
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:164563
Cellular Component	GO:0005802	trans-Golgi network	ISO	J:164563
Cellular Component	GO:0005802	trans-Golgi network	IDA	J:204172
Biological Process	GO:0030036	actin cytoskeleton organization	IMP	J:216094
Biological Process	GO:0001508	action potential	IMP	J:111204
Biological Process	GO:0006865	amino acid transport	IMP	J:111204
Biological Process	GO:0042987	amyloid precursor protein catabolic process	ISO	J:164563
Biological Process	GO:0008306	associative learning	IMP	J:98844
Biological Process	GO:0097352	autophagosome maturation	IMP	J:114863
Biological Process	GO:0061909	autophagosome-lysosome fusion	IMP	J:226833
Biological Process	GO:0043534	blood vessel endothelial cell migration	IMP	J:216094
Biological Process	GO:0006897	endocytosis	IMP	J:216094
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:216094
Biological Process	GO:0046474	glycerophospholipid biosynthetic process	ISO	J:164563
Biological Process	GO:0046836	glycolipid transport	ISO	J:164563
Biological Process	GO:0090160	Golgi to lysosome transport	ISO	J:164563
Biological Process	GO:0009992	intracellular water homeostasis	IMP	J:160849
Biological Process	GO:0035235	ionotropic glutamate receptor signaling pathway	IMP	J:111283
Biological Process	GO:1903826	L-arginine transmembrane transport	ISO	J:164563
Biological Process	GO:0007611	learning or memory	IMP	J:254965
Biological Process	GO:0007042	lysosomal lumen acidification	ISO	J:164563
Biological Process	GO:0007042	lysosomal lumen acidification	IBA	J:265628
Biological Process	GO:0035752	lysosomal lumen pH elevation	ISO	J:164563
Biological Process	GO:1905146	lysosomal protein catabolic process	IMP	J:125194
Biological Process	GO:1905146	lysosomal protein catabolic process	IMP	J:58230
Biological Process	GO:0007040	lysosome organization	IBA	J:265628
Biological Process	GO:0007040	lysosome organization	IMP	J:95873
Biological Process	GO:0007040	lysosome organization	IMP	J:55232
Biological Process	GO:0007040	lysosome organization	IMP	J:58230
Biological Process	GO:0007040	lysosome organization	IMP	J:57155
Biological Process	GO:0016236	macroautophagy	IMP	J:114863
Biological Process	GO:0016236	macroautophagy	IMP	J:114863
Biological Process	GO:0016236	macroautophagy	IMP	J:114863
Biological Process	GO:0061024	membrane organization	IMP	J:95873
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:282684
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043086	negative regulation of catalytic activity	IMP	J:128711
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IDA	J:117797
Biological Process	GO:0045861	negative regulation of proteolysis	IMP	J:58230
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:111283
Biological Process	GO:0042133	neurotransmitter metabolic process	IMP	J:105697
Biological Process	GO:0042133	neurotransmitter metabolic process	IMP	J:105697
Biological Process	GO:0090384	phagosome-lysosome docking	IMP	J:226833
Biological Process	GO:0090385	phagosome-lysosome fusion	IMP	J:226833
Biological Process	GO:0044857	plasma membrane raft organization	IMP	J:204172
Biological Process	GO:2001288	positive regulation of caveolin-mediated endocytosis	IMP	J:204172
Biological Process	GO:0042998	positive regulation of Golgi to plasma membrane protein transport	IMP	J:204172
Biological Process	GO:0048549	positive regulation of pinocytosis	IMP	J:216094
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IMP	J:216094
Biological Process	GO:0072657	protein localization to membrane	IMP	J:216094
Biological Process	GO:0072659	protein localization to plasma membrane	IMP	J:216094
Biological Process	GO:0006468	protein phosphorylation	IMP	J:216094
Biological Process	GO:0016485	protein processing	IMP	J:95873
Biological Process	GO:0006898	receptor-mediated endocytosis	ISO	J:164563
Biological Process	GO:1900079	regulation of arginine biosynthetic process	IMP	J:164047
Biological Process	GO:1901096	regulation of autophagosome maturation	IMP	J:226833
Biological Process	GO:0016243	regulation of autophagosome size	IMP	J:282622
Biological Process	GO:0010506	regulation of autophagy	IMP	J:233445
Biological Process	GO:0106049	regulation of cellular response to osmotic stress	ISO	J:164563
Biological Process	GO:0051493	regulation of cytoskeleton organization	ISO	J:164563
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	IDA	J:117797
Biological Process	GO:0010762	regulation of fibroblast migration	ISO	J:164563
Biological Process	GO:0051489	regulation of filopodium assembly	IMP	J:216094
Biological Process	GO:0010468	regulation of gene expression	ISO	J:128711
Biological Process	GO:1905244	regulation of modification of synaptic structure	IMP	J:266792
Biological Process	GO:1905162	regulation of phagosome maturation	IMP	J:226833
Biological Process	GO:1903076	regulation of protein localization to plasma membrane	IMP	J:138856
Biological Process	GO:0070613	regulation of protein processing	ISO	J:164563
Biological Process	GO:0048172	regulation of short-term neuronal synaptic plasticity	IMP	J:254965
Biological Process	GO:0048172	regulation of short-term neuronal synaptic plasticity	IMP	J:266792
Biological Process	GO:0032228	regulation of synaptic transmission, GABAergic	IMP	J:254965
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	IMP	J:254965
Biological Process	GO:0036359	renal potassium excretion	IMP	J:160849
Biological Process	GO:0047496	vesicle transport along microtubule	ISO	J:164563