Sox17 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Sox17
SRY (sex determining region Y)-box 17
MGI:107543

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:91550
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:33784
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:217510
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:150354
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:197716
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:92559
Molecular Function	GO:0005515	protein binding	IPI	J:168158
Molecular Function	GO:0005515	protein binding	IPI	J:129040
Molecular Function	GO:0005515	protein binding	IPI	J:197716
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:33784
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:168158
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:168289
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:150354
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:156932
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:33784
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:217510
Cellular Component	GO:0005634	nucleus	IDA	J:129040
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:109303
Cellular Component	GO:0005634	nucleus	IDA	J:156932
Cellular Component	GO:0005634	nucleus	IDA	J:199456
Cellular Component	GO:0005634	nucleus	IDA	J:170416
Cellular Component	GO:0005634	nucleus	IDA	J:33784
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:164563
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:197716
Biological Process	GO:0009653	anatomical structure morphogenesis	IBA	J:265628
Biological Process	GO:0001525	angiogenesis	IBA	J:265628
Biological Process	GO:0001525	angiogenesis	IGI	J:113127
Biological Process	GO:0060913	cardiac cell fate determination	ISO	J:164563
Biological Process	GO:0003142	cardiogenic plate morphogenesis	IMP	J:170493
Biological Process	GO:0042074	cell migration involved in gastrulation	IMP	J:170416
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IDA	J:163558
Biological Process	GO:0061009	common bile duct development	IMP	J:156731
Biological Process	GO:0048617	embryonic foregut morphogenesis	IMP	J:170493
Biological Process	GO:0048617	embryonic foregut morphogenesis	IMP	J:151981
Biological Process	GO:0048617	embryonic foregut morphogenesis	IMP	J:155850
Biological Process	GO:0048617	embryonic foregut morphogenesis	IMP	J:151981
Biological Process	GO:0035050	embryonic heart tube development	IGI	J:123026
Biological Process	GO:0003143	embryonic heart tube morphogenesis	IMP	J:170493
Biological Process	GO:0048568	embryonic organ development	IMP	J:156731
Biological Process	GO:0060956	endocardial cell differentiation	IGI	J:123026
Biological Process	GO:0060214	endocardium formation	IGI	J:123026
Biological Process	GO:0007492	endoderm development	IMP	J:75946
Biological Process	GO:0007492	endoderm development	IMP	J:170416
Biological Process	GO:0007492	endoderm development	IMP	J:156731
Biological Process	GO:0001706	endoderm formation	ISO	J:164563
Biological Process	GO:0035987	endodermal cell differentiation	IDA	J:127789
Biological Process	GO:0007493	endodermal cell fate determination	IDA	J:159322
Biological Process	GO:0001714	endodermal cell fate specification	IMP	J:170493
Biological Process	GO:0061031	endodermal digestive tract morphogenesis	IMP	J:170493
Biological Process	GO:0061010	gallbladder development	IMP	J:156731
Biological Process	GO:0007369	gastrulation	IMP	J:156932
Biological Process	GO:0010467	gene expression	IMP	J:127789
Biological Process	GO:0010467	gene expression	IMP	J:156932
Biological Process	GO:0007507	heart development	IBA	J:265628
Biological Process	GO:0001947	heart looping	IMP	J:123050
Biological Process	GO:0001947	heart looping	IMP	J:123026
Biological Process	GO:0001828	inner cell mass cellular morphogenesis	IMP	J:170416
Biological Process	GO:0001656	metanephros development	ISO	J:164563
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IMP	J:129040
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:164563
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	IDA	J:168158
Biological Process	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development	IMP	J:120067
Biological Process	GO:0003151	outflow tract morphogenesis	IGI	J:123026
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:150354
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:92559
Biological Process	GO:1903226	positive regulation of endodermal cell differentiation	IDA	J:127789
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:127789
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:156932
Biological Process	GO:0045732	positive regulation of protein catabolic process	IDA	J:168158
Biological Process	GO:2000738	positive regulation of stem cell differentiation	IMP	J:156932
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:33784
Biological Process	GO:0031648	protein destabilization	ISO	J:164563
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:2000043	regulation of cardiac cell fate specification	IMP	J:120067
Biological Process	GO:0045595	regulation of cell differentiation	IMP	J:170416
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:168158
Biological Process	GO:0045995	regulation of embryonic development	IMP	J:75946
Biological Process	GO:2000035	regulation of stem cell division	IMP	J:156932
Biological Process	GO:0072091	regulation of stem cell proliferation	IDA	J:160232
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:170493
Biological Process	GO:0021903	rostrocaudal neural tube patterning	IMP	J:156731
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	IDA	J:155850
Biological Process	GO:0007283	spermatogenesis	IDA	J:33784
Biological Process	GO:0048863	stem cell differentiation	IMP	J:156932
Biological Process	GO:0048863	stem cell differentiation	IMP	J:156932
Biological Process	GO:0048866	stem cell fate specification	IDA	J:160232
Biological Process	GO:0072189	ureter development	ISO	J:164563
Biological Process	GO:0001570	vasculogenesis	IBA	J:265628
Biological Process	GO:0001570	vasculogenesis	IGI	J:113127
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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