GO Annotations Graph

• Symbol: Epx
• Name: eosinophil peroxidase
• ID: MGI:107569

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0020037	heme binding	IEA	J:72247
Molecular Function	GO:0140825	lactoperoxidase activity	IEA	J:72245
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0004601	peroxidase activity	IBA	J:265628
Molecular Function	GO:0004601	peroxidase activity	IDA	J:34899
Molecular Function	GO:0004601	peroxidase activity	IDA	J:112446
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Biological Process	GO:0006952	defense response	IEA	J:72247
Biological Process	GO:0042742	defense response to bacterium	IBA	J:265628
Biological Process	GO:0002215	defense response to nematode	IMP	J:112446
Biological Process	GO:0072677	eosinophil migration	IMP	J:112446
Biological Process	GO:0042744	hydrogen peroxide catabolic process	IEA	J:60000
Biological Process	GO:0032613	interleukin-10 production	IMP	J:112446
Biological Process	GO:0032633	interleukin-4 production	IMP	J:112446
Biological Process	GO:0032634	interleukin-5 production	IMP	J:112446
Biological Process	GO:0010934	macrophage cytokine production	IMP	J:112446
Biological Process	GO:0032693	negative regulation of interleukin-10 production	IMP	J:112446
Biological Process	GO:0032714	negative regulation of interleukin-5 production	IMP	J:112446
Biological Process	GO:0010936	negative regulation of macrophage cytokine production	IMP	J:112446
Biological Process	GO:0032753	positive regulation of interleukin-4 production	IMP	J:112446
Biological Process	GO:0006979	response to oxidative stress	IEA	J:72247