GO Annotations Graph

• Symbol: Ifnar1
• Name: interferon (alpha and beta) receptor 1
• ID: MGI:107658

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019955	cytokine binding	ISO	J:164563
Molecular Function	GO:0004904	interferon receptor activity	IMP	J:235021
Molecular Function	GO:0004904	interferon receptor activity	IMP	J:100999
Molecular Function	GO:0008269	JAK pathway signal transduction adaptor activity	ISO	J:164563
Molecular Function	GO:0004637	phosphoribosylamine-glycine ligase activity	IEA	J:72245
Molecular Function	GO:0019962	type I interferon binding	IPI	J:208239
Molecular Function	GO:0004905	type I interferon receptor activity	ISO	J:164563
Molecular Function	GO:0004905	type I interferon receptor activity	IDA	J:208239
Molecular Function	GO:0004905	type I interferon receptor activity	IMP	J:228118
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IDA	J:228118
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-912695
Biological Process	GO:0035457	cellular response to interferon-alpha	IMP	J:228118
Biological Process	GO:0035458	cellular response to interferon-beta	ISO	J:164563
Biological Process	GO:0019221	cytokine-mediated signaling pathway	ISO	J:155856
Biological Process	GO:0051607	defense response to virus	IMP	J:235021
Biological Process	GO:0051607	defense response to virus	IMP	J:143981
Biological Process	GO:0010467	gene expression	IMP	J:290078
Biological Process	GO:1901857	positive regulation of cellular respiration	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:219043
Biological Process	GO:0032728	positive regulation of interferon-beta production	IMP	J:219043
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	IMP	J:205949
Biological Process	GO:0032729	positive regulation of type II interferon production	IGI	J:120927
Biological Process	GO:0007259	receptor signaling pathway via JAK-STAT	ISO	J:164563
Biological Process	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	IMP	J:173334
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:208239
Biological Process	GO:0042110	T cell activation	IGI	J:120927
Biological Process	GO:0032606	type I interferon production	IMP	J:97662
Biological Process	GO:0060337	type I interferon-mediated signaling pathway	IMP	J:235021
Biological Process	GO:0060337	type I interferon-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0060337	type I interferon-mediated signaling pathway	IDA	J:208239
Biological Process	GO:0060337	type I interferon-mediated signaling pathway	IMP	J:228118
Biological Process	GO:0032609	type II interferon production	IGI	J:120927