GO Annotations Graph

• Symbol: Abcg1
• Name: ATP binding cassette subfamily G member 1
• ID: MGI:107704

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0034041	ABC-type sterol transporter activity	ISO	J:164563
Molecular Function	GO:0034041	ABC-type sterol transporter activity	IBA	J:265628
Molecular Function	GO:0140359	ABC-type transporter activity	IEA	J:72247
Molecular Function	GO:0043531	ADP binding	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0120020	cholesterol transfer activity	ISO	J:164563
Molecular Function	GO:0140328	floppase activity	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0090554	phosphatidylcholine floppase activity	ISO	J:164563
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0019534	toxin transmembrane transporter activity	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005768	endosome	IDA	J:128847
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:150920
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0055037	recycling endosome	IDA	J:150920
Biological Process	GO:0042987	amyloid precursor protein catabolic process	ISO	J:164563
Biological Process	GO:0071403	cellular response to high density lipoprotein particle stimulus	IDA	J:91401
Biological Process	GO:0033344	cholesterol efflux	IMP	J:220507
Biological Process	GO:0033344	cholesterol efflux	IMP	J:150920
Biological Process	GO:0033344	cholesterol efflux	ISO	J:164563
Biological Process	GO:0042632	cholesterol homeostasis	ISO	J:164563
Biological Process	GO:0042632	cholesterol homeostasis	IBA	J:265628
Biological Process	GO:0008203	cholesterol metabolic process	ISO	J:164563
Biological Process	GO:0030301	cholesterol transport	IDA	J:94492
Biological Process	GO:0034436	glycoprotein transport	ISO	J:164563
Biological Process	GO:0034375	high-density lipoprotein particle remodeling	IMP	J:220507
Biological Process	GO:0034375	high-density lipoprotein particle remodeling	IMP	J:150920
Biological Process	GO:0032367	intracellular cholesterol transport	ISO	J:164563
Biological Process	GO:0006869	lipid transport	IEA	J:60000
Biological Process	GO:0034374	low-density lipoprotein particle remodeling	IMP	J:150920
Biological Process	GO:0010888	negative regulation of lipid storage	IMP	J:150920
Biological Process	GO:0010745	negative regulation of macrophage derived foam cell differentiation	IC	J:150920
Biological Process	GO:0033700	phospholipid efflux	ISO	J:164563
Biological Process	GO:0055091	phospholipid homeostasis	ISO	J:164563
Biological Process	GO:1902004	positive regulation of amyloid-beta formation	ISO	J:164563
Biological Process	GO:0045542	positive regulation of cholesterol biosynthetic process	IMP	J:128847
Biological Process	GO:0010875	positive regulation of cholesterol efflux	IDA	J:91401
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	ISO	J:155856
Biological Process	GO:0050714	positive regulation of protein secretion	ISO	J:164563
Biological Process	GO:1904411	positive regulation of secretory granule organization	ISO	J:155856
Biological Process	GO:0090181	regulation of cholesterol metabolic process	IMP	J:150920
Biological Process	GO:0033993	response to lipid	ISO	J:164563
Biological Process	GO:0043691	reverse cholesterol transport	IMP	J:123959
Biological Process	GO:0055085	transmembrane transport	IBA	J:265628