GO Annotations Graph

• Symbol: Igtp
• Name: interferon gamma induced GTPase
• ID: MGI:107729

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051434	BH3 domain binding	ISO	J:164563
Molecular Function	GO:0050700	CARD domain binding	ISO	J:164563
Molecular Function	GO:1901612	cardiolipin binding	ISO	J:164563
Molecular Function	GO:0003925	G protein activity	ISO	J:164563
Molecular Function	GO:0003924	GTPase activity	IDA	J:333133
Molecular Function	GO:0003924	GTPase activity	ISO	J:164563
Molecular Function	GO:0003924	GTPase activity	IBA	J:265628
Molecular Function	GO:0003924	GTPase activity	IDA	J:34886
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	ISO	J:164563
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	ISO	J:164563
Cellular Component	GO:0000421	autophagosome membrane	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:34886
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:333133
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0000139	Golgi membrane	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Biological Process	GO:0000045	autophagosome assembly	ISO	J:164563
Biological Process	GO:0061762	CAMKK-AMPK signaling cascade	ISO	J:164563
Biological Process	GO:0043374	CD8-positive, alpha-beta T cell differentiation	IDA	J:229266
Biological Process	GO:0035458	cellular response to interferon-beta	IBA	J:265628
Biological Process	GO:0035458	cellular response to interferon-beta	IDA	J:145965
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ISO	J:164563
Biological Process	GO:0071346	cellular response to type II interferon	IDA	J:333134
Biological Process	GO:0071346	cellular response to type II interferon	IDA	J:333135
Biological Process	GO:0071346	cellular response to type II interferon	IDA	J:141174
Biological Process	GO:0098586	cellular response to virus	ISO	J:164563
Biological Process	GO:0051715	cytolysis in another organism	IDA	J:124556
Biological Process	GO:0006952	defense response	IBA	J:265628
Biological Process	GO:0042742	defense response to bacterium	ISO	J:164563
Biological Process	GO:0050829	defense response to Gram-negative bacterium	ISO	J:164563
Biological Process	GO:0042832	defense response to protozoan	IMP	J:333134
Biological Process	GO:0042832	defense response to protozoan	IMP	J:59891
Biological Process	GO:0042832	defense response to protozoan	IDA	J:333135
Biological Process	GO:0042832	defense response to protozoan	IDA	J:141174
Biological Process	GO:0045087	innate immune response	IMP	J:333134
Biological Process	GO:0045087	innate immune response	IMP	J:59891
Biological Process	GO:0045087	innate immune response	ISO	J:164563
Biological Process	GO:0160049	negative regulation of cGAS/STING signaling pathway	ISO	J:164563
Biological Process	GO:0050687	negative regulation of defense response to virus	ISO	J:164563
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0050728	negative regulation of inflammatory response	ISO	J:164563
Biological Process	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly	ISO	J:164563
Biological Process	GO:1903898	negative regulation of PERK-mediated unfolded protein response	IDA	J:333136
Biological Process	GO:0032480	negative regulation of type I interferon production	ISO	J:164563
Biological Process	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	ISO	J:164563
Biological Process	GO:1901098	positive regulation of autophagosome maturation	ISO	J:164563
Biological Process	GO:1901098	positive regulation of autophagosome maturation	IDA	J:124556
Biological Process	GO:0010508	positive regulation of autophagy	ISO	J:164563
Biological Process	GO:1905673	positive regulation of lysosome organization	ISO	J:164563
Biological Process	GO:0090141	positive regulation of mitochondrial fission	ISO	J:164563
Biological Process	GO:1901526	positive regulation of mitophagy	ISO	J:164563
Biological Process	GO:1901526	positive regulation of mitophagy	ISO	J:164563
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0010800	positive regulation of peptidyl-threonine phosphorylation	ISO	J:164563
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	ISO	J:164563
Biological Process	GO:0060335	positive regulation of type II interferon-mediated signaling pathway	ISO	J:164563
Biological Process	GO:1904417	positive regulation of xenophagy	ISO	J:164563
Biological Process	GO:0031648	protein destabilization	ISO	J:164563
Biological Process	GO:0061739	protein lipidation involved in autophagosome assembly	ISO	J:164563
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0071211	protein targeting to vacuole involved in autophagy	ISO	J:164563
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0061635	regulation of protein complex stability	ISO	J:164563
Biological Process	GO:0043254	regulation of protein-containing complex assembly	ISO	J:164563