GO Annotations Graph

• Symbol: Dync2h1
• Name: dynein cytoplasmic 2 heavy chain 1
• ID: MGI:107736

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0045505	dynein intermediate chain binding	IEA	J:72247
Molecular Function	GO:0051959	dynein light intermediate chain binding	ISO	J:155856
Molecular Function	GO:0008569	minus-end-directed microtubule motor activity	ISO	J:164563
Molecular Function	GO:0008569	minus-end-directed microtubule motor activity	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Cellular Component	GO:0045177	apical part of cell	IDA	J:172889
Cellular Component	GO:0005930	axoneme	IDA	J:172889
Cellular Component	GO:0005930	axoneme	IBA	J:265628
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005929	cilium	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005868	cytoplasmic dynein complex	ISO	J:164563
Cellular Component	GO:0005868	cytoplasmic dynein complex	IBA	J:265628
Cellular Component	GO:0005868	cytoplasmic dynein complex	ISM	J:43700
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0030286	dynein complex	IEA	J:72247
Cellular Component	GO:0030286	dynein complex	IEA	J:60000
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005874	microtubule	ISO	J:164563
Cellular Component	GO:0031514	motile cilium	IDA	J:172889
Cellular Component	GO:0031514	motile cilium	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0030030	cell projection organization	IEA	J:60000
Biological Process	GO:0060271	cilium assembly	IBA	J:265628
Biological Process	GO:0060271	cilium assembly	IMP	J:100466
Biological Process	GO:0060271	cilium assembly	IMP	J:103514
Biological Process	GO:0060271	cilium assembly	IMP	J:103514
Biological Process	GO:0060271	cilium assembly	IMP	J:103514
Biological Process	GO:0060976	coronary vasculature development	IMP	J:222159
Biological Process	GO:0007368	determination of left/right symmetry	IMP	J:103514
Biological Process	GO:0007368	determination of left/right symmetry	IMP	J:98216
Biological Process	GO:0007368	determination of left/right symmetry	IMP	J:100466
Biological Process	GO:0007368	determination of left/right symmetry	IMP	J:222159
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:103514
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:100466
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:98216
Biological Process	GO:0009953	dorsal/ventral pattern formation	IGI	J:188764
Biological Process	GO:0009953	dorsal/ventral pattern formation	IGI	J:188764
Biological Process	GO:0009953	dorsal/ventral pattern formation	IGI	J:188764
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:103514
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:103514
Biological Process	GO:0030900	forebrain development	IMP	J:103514
Biological Process	GO:0007030	Golgi organization	ISO	J:164563
Biological Process	GO:0007507	heart development	IMP	J:222159
Biological Process	GO:0035721	intraciliary retrograde transport	IBA	J:265628
Biological Process	GO:0035721	intraciliary retrograde transport	IMP	J:138139
Biological Process	GO:0001822	kidney development	IMP	J:231949
Biological Process	GO:0007018	microtubule-based movement	IEA	J:72247
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0030182	neuron differentiation	IMP	J:188764
Biological Process	GO:0030182	neuron differentiation	IMP	J:188764
Biological Process	GO:1905515	non-motile cilium assembly	IMP	J:185270
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	IMP	J:138139
Biological Process	GO:0061512	protein localization to cilium	IMP	J:103514
Biological Process	GO:0016485	protein processing	IMP	J:100466
Biological Process	GO:0016485	protein processing	IMP	J:103514
Biological Process	GO:0021522	spinal cord motor neuron differentiation	IGI	J:188764
Biological Process	GO:0021522	spinal cord motor neuron differentiation	IGI	J:188764
Biological Process	GO:0021522	spinal cord motor neuron differentiation	IGI	J:188764