GO Annotations Graph

• Symbol: Dctn1
• Name: dynactin 1
• ID: MGI:107745

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0008017	microtubule binding	ISO	J:155856
Molecular Function	GO:0008017	microtubule binding	ISO	J:164563
Molecular Function	GO:0008017	microtubule binding	IDA	J:112743
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:138311
Molecular Function	GO:0005515	protein binding	IPI	J:108467
Molecular Function	GO:0005515	protein binding	IPI	J:200276
Molecular Function	GO:0005515	protein binding	IPI	J:273640
Molecular Function	GO:0005515	protein binding	IPI	J:86328
Molecular Function	GO:0005515	protein binding	IPI	J:207807
Molecular Function	GO:0005515	protein binding	IPI	J:236210
Molecular Function	GO:0005515	protein binding	IPI	J:207807
Molecular Function	GO:0005515	protein binding	IPI	J:91294
Molecular Function	GO:0005515	protein binding	IPI	J:180994
Molecular Function	GO:0005515	protein binding	IPI	J:91294
Molecular Function	GO:0005515	protein binding	IPI	J:133434
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0015631	tubulin binding	ISO	J:164563
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0005938	cell cortex	ISO	J:164563
Cellular Component	GO:0005938	cell cortex	ISO	J:164563
Cellular Component	GO:0099738	cell cortex region	ISO	J:164563
Cellular Component	GO:0031252	cell leading edge	IDA	J:133434
Cellular Component	GO:0120103	centriolar subdistal appendage	ISO	J:164563
Cellular Component	GO:0005814	centriole	IDA	J:207807
Cellular Component	GO:0005814	centriole	ISO	J:164563
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0036064	ciliary basal body	IDA	J:124167
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005868	cytoplasmic dynein complex	ISO	J:155856
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0030286	dynein complex	IEA	J:60000
Cellular Component	GO:0045171	intercellular bridge	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	IBA	J:265628
Cellular Component	GO:0005874	microtubule	ISO	J:164563
Cellular Component	GO:0005875	microtubule associated complex	ISO	J:164563
Cellular Component	GO:0005875	microtubule associated complex	IBA	J:265628
Cellular Component	GO:0015630	microtubule cytoskeleton	ISO	J:164563
Cellular Component	GO:0035371	microtubule plus-end	IDA	J:112743
Cellular Component	GO:0035371	microtubule plus-end	ISO	J:164563
Cellular Component	GO:0072686	mitotic spindle	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	ISO	J:164563
Cellular Component	GO:0005635	nuclear envelope	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0032991	protein-containing complex	IDA	J:197986
Cellular Component	GO:0030904	retromer complex	ISO	J:164563
Cellular Component	GO:0005819	spindle	ISO	J:164563
Cellular Component	GO:0000922	spindle pole	IDA	J:229900
Cellular Component	GO:0000922	spindle pole	ISO	J:164563
Cellular Component	GO:0000922	spindle pole	IBA	J:265628
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0010457	centriole-centriole cohesion	ISO	J:164563
Biological Process	GO:0000132	establishment of mitotic spindle orientation	ISO	J:164563
Biological Process	GO:0000132	establishment of mitotic spindle orientation	IBA	J:265628
Biological Process	GO:0032402	melanosome transport	IMP	J:197308
Biological Process	GO:0034454	microtubule anchoring at centrosome	ISO	J:164563
Biological Process	GO:0061744	motor behavior	ISO	J:164563
Biological Process	GO:0007528	neuromuscular junction development	ISO	J:164563
Biological Process	GO:0050905	neuromuscular process	ISO	J:164563
Biological Process	GO:0070050	neuron cellular homeostasis	ISO	J:164563
Biological Process	GO:1990535	neuron projection maintenance	ISO	J:164563
Biological Process	GO:1905515	non-motile cilium assembly	ISO	J:164563
Biological Process	GO:0051081	nuclear membrane disassembly	ISO	J:164563
Biological Process	GO:0007097	nuclear migration	IBA	J:265628
Biological Process	GO:0090063	positive regulation of microtubule nucleation	ISO	J:164563
Biological Process	GO:0031116	positive regulation of microtubule polymerization	ISO	J:164563
Biological Process	GO:1904398	positive regulation of neuromuscular junction development	ISO	J:164563
Biological Process	GO:0060236	regulation of mitotic spindle organization	ISO	J:164563
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	ISO	J:164563
Biological Process	GO:0021517	ventral spinal cord development	ISO	J:164563