GO Annotations Graph

• Symbol: Neurod2
• Name: neurogenic differentiation 2
• ID: MGI:107755

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:102471
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:53595
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:164132
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IBA	J:265628
Molecular Function	GO:0070888	E-box binding	IDA	J:87366
Molecular Function	GO:0070888	E-box binding	IDA	J:134786
Molecular Function	GO:0070888	E-box binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:172950
Molecular Function	GO:0005515	protein binding	IPI	J:134786
Molecular Function	GO:0005515	protein binding	IPI	J:134786
Molecular Function	GO:0005515	protein binding	IPI	J:134786
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0046982	protein heterodimerization activity	IDA	J:134786
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:53595
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:164132
Cellular Component	GO:0005634	nucleus	IDA	J:172992
Cellular Component	GO:0005634	nucleus	IDA	J:172912
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0008306	associative learning	IMP	J:102471
Biological Process	GO:0061564	axon development	IBA	J:265628
Biological Process	GO:0001662	behavioral fear response	IMP	J:102471
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0071277	cellular response to calcium ion	IDA	J:107599
Biological Process	GO:0071257	cellular response to electrical stimulus	IDA	J:107599
Biological Process	GO:0021695	cerebellar cortex development	IMP	J:107599
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:2000297	negative regulation of synapse maturation	IDA	J:172950
Biological Process	GO:0007399	nervous system development	IEA	J:72247
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0048666	neuron development	IMP	J:102471
Biological Process	GO:0050850	positive regulation of calcium-mediated signaling	IDA	J:107599
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	IDA	J:87366
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	IDA	J:107599
Biological Process	GO:0045666	positive regulation of neuron differentiation	IDA	J:172912
Biological Process	GO:0045666	positive regulation of neuron differentiation	IDA	J:134786
Biological Process	GO:0045666	positive regulation of neuron differentiation	IDA	J:164132
Biological Process	GO:0045666	positive regulation of neuron differentiation	IDA	J:172992
Biological Process	GO:0090129	positive regulation of synapse maturation	IMP	J:107599
Biological Process	GO:0031915	positive regulation of synaptic plasticity	IDA	J:172950
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:53595
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0016567	protein ubiquitination	IDA	J:172950
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0045664	regulation of neuron differentiation	IEA	J:72247
Biological Process	GO:0090128	regulation of synapse maturation	IEA	J:72247
Biological Process	GO:0007423	sensory organ development	IBA	J:265628