GO Annotations Graph

• Symbol: Mesp1
• Name: mesoderm posterior 1
• ID: MGI:107785

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:159135
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:145669
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IMP	J:145669
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IMP	J:145669
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:145669
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:159135
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0003210	cardiac atrium formation	ISO	J:164563
Biological Process	GO:0060913	cardiac cell fate determination	IDA	J:159135
Biological Process	GO:0055007	cardiac muscle cell differentiation	ISO	J:164563
Biological Process	GO:0060947	cardiac vascular smooth muscle cell differentiation	ISO	J:164563
Biological Process	GO:0003211	cardiac ventricle formation	ISO	J:164563
Biological Process	GO:0003259	cardioblast anterior-lateral migration	IEP	J:145669
Biological Process	GO:0003260	cardioblast migration	IMP	J:55840
Biological Process	GO:0060975	cardioblast migration to the midline involved in heart field formation	IMP	J:55840
Biological Process	GO:0003143	embryonic heart tube morphogenesis	IMP	J:55840
Biological Process	GO:0045446	endothelial cell differentiation	ISO	J:164563
Biological Process	GO:0007369	gastrulation	IEP	J:35774
Biological Process	GO:0010467	gene expression	IMP	J:207590
Biological Process	GO:0003241	growth involved in heart morphogenesis	IMP	J:55840
Biological Process	GO:0001947	heart looping	IMP	J:55840
Biological Process	GO:0003007	heart morphogenesis	IBA	J:265628
Biological Process	GO:0003007	heart morphogenesis	IMP	J:55840
Biological Process	GO:0048368	lateral mesoderm development	IEP	J:55840
Biological Process	GO:0001707	mesoderm formation	IBA	J:265628
Biological Process	GO:0008078	mesodermal cell migration	IGI	J:55840
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:159135
Biological Process	GO:0042664	negative regulation of endodermal cell fate specification	IDA	J:159135
Biological Process	GO:0042662	negative regulation of mesodermal cell fate specification	IDA	J:159135
Biological Process	GO:0022008	neurogenesis	ISO	J:164563
Biological Process	GO:0007219	Notch signaling pathway	IEA	J:60000
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:159135
Biological Process	GO:0090082	positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway	IDA	J:145669
Biological Process	GO:0070368	positive regulation of hepatocyte differentiation	IDA	J:159135
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	IDA	J:159135
Biological Process	GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	IDA	J:159135
Biological Process	GO:0051155	positive regulation of striated muscle cell differentiation	IDA	J:159135
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:145669
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:145669
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0003139	secondary heart field specification	IDA	J:159135
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	IDA	J:155850
Biological Process	GO:0060921	sinoatrial node cell differentiation	ISO	J:164563
Biological Process	GO:0003236	sinus venosus morphogenesis	IMP	J:55840
Biological Process	GO:0032525	somite rostral/caudal axis specification	IBA	J:265628