GO Annotations Graph

• Symbol: Has2
• Name: hyaluronan synthase 2
• ID: MGI:107821

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016757	glycosyltransferase activity	IEA	J:60000
Molecular Function	GO:0050501	hyaluronan synthase activity	ISO	J:155856
Molecular Function	GO:0050501	hyaluronan synthase activity	ISO	J:164563
Molecular Function	GO:0050501	hyaluronan synthase activity	IBA	J:265628
Molecular Function	GO:0050501	hyaluronan synthase activity	IDA	J:200337
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:219166
Cellular Component	GO:0031410	cytoplasmic vesicle	IDA	J:219166
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:1903561	extracellular vesicle	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:200337
Cellular Component	GO:0044853	plasma membrane raft	IDA	J:184361
Biological Process	GO:0036302	atrioventricular canal development	IMP	J:63748
Biological Process	GO:0060349	bone morphogenesis	IMP	J:167831
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	ISO	J:164563
Biological Process	GO:0090500	endocardial cushion to mesenchymal transition	IMP	J:63748
Biological Process	GO:0085029	extracellular matrix assembly	IDA	J:200337
Biological Process	GO:0085029	extracellular matrix assembly	IBA	J:265628
Biological Process	GO:0045226	extracellular polysaccharide biosynthetic process	IDA	J:200337
Biological Process	GO:0045226	extracellular polysaccharide biosynthetic process	IBA	J:265628
Biological Process	GO:0030213	hyaluronan biosynthetic process	IMP	J:63748
Biological Process	GO:0030213	hyaluronan biosynthetic process	ISO	J:164563
Biological Process	GO:0030213	hyaluronan biosynthetic process	IBA	J:265628
Biological Process	GO:0030213	hyaluronan biosynthetic process	IDA	J:200337
Biological Process	GO:0030213	hyaluronan biosynthetic process	IDA	J:35498
Biological Process	GO:0030212	hyaluronan metabolic process	IMP	J:167831
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:1900127	positive regulation of hyaluronan biosynthetic process	ISO	J:155856
Biological Process	GO:0051549	positive regulation of keratinocyte migration	ISO	J:155856
Biological Process	GO:0010838	positive regulation of keratinocyte proliferation	ISO	J:155856
Biological Process	GO:1900625	positive regulation of monocyte aggregation	ISO	J:164563
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	ISO	J:155856
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	ISO	J:155856
Biological Process	GO:1901201	regulation of extracellular matrix assembly	ISO	J:155856
Biological Process	GO:0001570	vasculogenesis	IMP	J:63748