GO Annotations Graph

• Symbol: Cd36
• Name: CD36 molecule
• ID: MGI:107899

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001540	amyloid-beta binding	ISO	J:164563
Molecular Function	GO:0005504	fatty acid binding	ISO	J:164563
Molecular Function	GO:0008035	high-density lipoprotein particle binding	IDA	J:88979
Molecular Function	GO:0008289	lipid binding	ISS	J:145844
Molecular Function	GO:0008289	lipid binding	ISO	J:164563
Molecular Function	GO:0071813	lipoprotein particle binding	ISO	J:164563
Molecular Function	GO:0070892	lipoteichoic acid immune receptor activity	IMP	J:100140
Molecular Function	GO:0005324	long-chain fatty acid transporter activity	ISO	J:164563
Molecular Function	GO:0030169	low-density lipoprotein particle binding	IMP	J:145844
Molecular Function	GO:0030169	low-density lipoprotein particle binding	IMP	J:80905
Molecular Function	GO:0030169	low-density lipoprotein particle binding	ISO	J:164563
Molecular Function	GO:0030169	low-density lipoprotein particle binding	IBA	J:265628
Molecular Function	GO:0005041	low-density lipoprotein particle receptor activity	ISO	J:164563
Molecular Function	GO:0005041	low-density lipoprotein particle receptor activity	IMP	J:145844
Molecular Function	GO:0005041	low-density lipoprotein particle receptor activity	IBA	J:265628
Molecular Function	GO:1901480	oleate transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0070538	oleic acid binding	ISO	J:155856
Molecular Function	GO:0150025	oxidised low-density lipoprotein particle receptor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:96478
Molecular Function	GO:0005515	protein binding	IPI	J:227372
Molecular Function	GO:0005515	protein binding	IPI	J:158401
Molecular Function	GO:0030296	protein tyrosine kinase activator activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0005044	scavenger receptor activity	ISO	J:164563
Molecular Function	GO:0005044	scavenger receptor activity	ISO	J:155856
Molecular Function	GO:0005044	scavenger receptor activity	IBA	J:265628
Molecular Function	GO:0015636	short-chain fatty acid transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0070053	thrombospondin receptor activity	ISO	J:155856
Molecular Function	GO:0035325	Toll-like receptor binding	ISO	J:164563
Molecular Function	GO:0050431	transforming growth factor beta binding	ISO	J:155856
Cellular Component	GO:0045177	apical part of cell	IDA	J:102503
Cellular Component	GO:0045177	apical part of cell	ISO	J:155856
Cellular Component	GO:0031526	brush border membrane	ISO	J:155856
Cellular Component	GO:0031526	brush border membrane	IDA	J:225484
Cellular Component	GO:0005901	caveola	ISO	J:164563
Cellular Component	GO:0005901	caveola	ISO	J:155856
Cellular Component	GO:0005901	caveola	IBA	J:265628
Cellular Component	GO:0071944	cell periphery	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISS	J:145844
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:100140
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:96018
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:96971
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:227372
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0045121	membrane raft	IDA	J:200795
Cellular Component	GO:0045121	membrane raft	IDA	J:96971
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-2187263
Cellular Component	GO:0005886	plasma membrane	IDA	J:165162
Cellular Component	GO:0005886	plasma membrane	IDA	J:96971
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0043235	receptor complex	ISO	J:164563
Cellular Component	GO:0042383	sarcolemma	ISO	J:155856
Biological Process	GO:1990000	amyloid fibril formation	IDA	J:205721
Biological Process	GO:0150094	amyloid-beta clearance by cellular catabolic process	ISO	J:164563
Biological Process	GO:0150094	amyloid-beta clearance by cellular catabolic process	IBA	J:265628
Biological Process	GO:0043277	apoptotic cell clearance	IMP	J:106377
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007166	cell surface receptor signaling pathway	IDA	J:166919
Biological Process	GO:1904646	cellular response to amyloid-beta	ISO	J:164563
Biological Process	GO:0071221	cellular response to bacterial lipopeptide	IMP	J:96018
Biological Process	GO:0071221	cellular response to bacterial lipopeptide	IMP	J:96018
Biological Process	GO:0071726	cellular response to diacyl bacterial lipopeptide	ISO	J:164563
Biological Process	GO:0071447	cellular response to hydroperoxide	IMP	J:166919
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IMP	J:100140
Biological Process	GO:0071223	cellular response to lipoteichoic acid	IMP	J:96018
Biological Process	GO:0071223	cellular response to lipoteichoic acid	IMP	J:100140
Biological Process	GO:0071223	cellular response to lipoteichoic acid	IMP	J:96018
Biological Process	GO:0071223	cellular response to lipoteichoic acid	IDA	J:96018
Biological Process	GO:0071404	cellular response to low-density lipoprotein particle stimulus	IDA	J:227372
Biological Process	GO:0140052	cellular response to oxidised low-density lipoprotein particle stimulus	ISO	J:164563
Biological Process	GO:0019934	cGMP-mediated signaling	ISO	J:164563
Biological Process	GO:0070508	cholesterol import	IMP	J:123605
Biological Process	GO:0030301	cholesterol transport	IMP	J:80905
Biological Process	GO:0050830	defense response to Gram-positive bacterium	IMP	J:96018
Biological Process	GO:0050830	defense response to Gram-positive bacterium	IMP	J:100140
Biological Process	GO:0097009	energy homeostasis	IMP	J:208972
Biological Process	GO:0006955	immune response	IEA	J:72247
Biological Process	GO:0032615	interleukin-12 production	IMP	J:100140
Biological Process	GO:0032635	interleukin-6 production	IMP	J:100140
Biological Process	GO:0050892	intestinal absorption	IMP	J:123605
Biological Process	GO:0030299	intestinal cholesterol absorption	IMP	J:123605
Biological Process	GO:0019915	lipid storage	IMP	J:145844
Biological Process	GO:0019915	lipid storage	ISO	J:164563
Biological Process	GO:0019915	lipid storage	IBA	J:265628
Biological Process	GO:0006869	lipid transport	IEA	J:60000
Biological Process	GO:1990379	lipid transport across blood-brain barrier	ISO	J:164563
Biological Process	GO:0042953	lipoprotein transport	IMP	J:145844
Biological Process	GO:0042953	lipoprotein transport	ISO	J:164563
Biological Process	GO:0042953	lipoprotein transport	IBA	J:265628
Biological Process	GO:0015911	long-chain fatty acid import across plasma membrane	ISO	J:164563
Biological Process	GO:0044539	long-chain fatty acid import into cell	IMP	J:123605
Biological Process	GO:0044539	long-chain fatty acid import into cell	ISO	J:164563
Biological Process	GO:0044539	long-chain fatty acid import into cell	IBA	J:265628
Biological Process	GO:0015909	long-chain fatty acid transport	ISO	J:164563
Biological Process	GO:0034383	low-density lipoprotein particle clearance	IMP	J:145844
Biological Process	GO:0034383	low-density lipoprotein particle clearance	ISO	J:164563
Biological Process	GO:0034383	low-density lipoprotein particle clearance	IBA	J:265628
Biological Process	GO:0055096	low-density lipoprotein particle mediated signaling	IDA	J:166919
Biological Process	GO:0010934	macrophage cytokine production	IMP	J:96018
Biological Process	GO:0010934	macrophage cytokine production	IMP	J:100140
Biological Process	GO:0000165	MAPK cascade	IMP	J:96018
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:166919
Biological Process	GO:0042308	negative regulation of protein import into nucleus	IMP	J:166919
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:166919
Biological Process	GO:0007263	nitric oxide mediated signal transduction	ISO	J:164563
Biological Process	GO:0150024	oxidised low-density lipoprotein particle clearance	ISO	J:164563
Biological Process	GO:0006910	phagocytosis, recognition	IDA	J:100140
Biological Process	GO:0034381	plasma lipoprotein particle clearance	IMP	J:80905
Biological Process	GO:0030194	positive regulation of blood coagulation	IMP	J:166919
Biological Process	GO:2000334	positive regulation of blood microparticle formation	IMP	J:166919
Biological Process	GO:0010942	positive regulation of cell death	ISO	J:164563
Biological Process	GO:0001954	positive regulation of cell-matrix adhesion	ISO	J:164563
Biological Process	GO:0010886	positive regulation of cholesterol storage	IMP	J:80905
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IMP	J:220343
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	IDA	J:225405
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IMP	J:225484
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:158401
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IMP	J:100140
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	IDA	J:205721
Biological Process	GO:0032735	positive regulation of interleukin-12 production	IMP	J:100140
Biological Process	GO:0032755	positive regulation of interleukin-6 production	IMP	J:100140
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	IMP	J:96018
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	IMP	J:100140
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	IMP	J:100140
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	IMP	J:100140
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	IMP	J:100140
Biological Process	GO:0010744	positive regulation of macrophage derived foam cell differentiation	ISO	J:164563
Biological Process	GO:0010744	positive regulation of macrophage derived foam cell differentiation	IMP	J:80905
Biological Process	GO:0010744	positive regulation of macrophage derived foam cell differentiation	IMP	J:145844
Biological Process	GO:0043410	positive regulation of MAPK cascade	IMP	J:96018
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	IGI	J:158401
Biological Process	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly	IDA	J:205721
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IDA	J:166919
Biological Process	GO:0060100	positive regulation of phagocytosis, engulfment	IDA	J:100140
Biological Process	GO:0060100	positive regulation of phagocytosis, engulfment	IMP	J:100140
Biological Process	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	IMP	J:158401
Biological Process	GO:2000379	positive regulation of reactive oxygen species metabolic process	IMP	J:166919
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	IMP	J:100140
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	IMP	J:96018
Biological Process	GO:0031623	receptor internalization	IDA	J:227372
Biological Process	GO:0006898	receptor-mediated endocytosis	ISO	J:164563
Biological Process	GO:0006898	receptor-mediated endocytosis	IBA	J:265628
Biological Process	GO:0098900	regulation of action potential	IMP	J:255338
Biological Process	GO:0043254	regulation of protein-containing complex assembly	ISO	J:164563
Biological Process	GO:2000121	regulation of removal of superoxide radicals	IMP	J:166919
Biological Process	GO:0034121	regulation of toll-like receptor signaling pathway	ISO	J:164563
Biological Process	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	IC	J:166919
Biological Process	GO:0009617	response to bacterium	IEP	J:190322
Biological Process	GO:0070542	response to fatty acid	IDA	J:225484
Biological Process	GO:0070542	response to fatty acid	IMP	J:208972
Biological Process	GO:0070543	response to linoleic acid	IDA	J:225405
Biological Process	GO:0033993	response to lipid	IDA	J:225484
Biological Process	GO:0035634	response to stilbenoid	IEP	J:169896
Biological Process	GO:0050909	sensory perception of taste	IDA	J:225405
Biological Process	GO:0015912	short-chain fatty acid transport	ISO	J:164563
Biological Process	GO:0034197	triglyceride transport	IMP	J:123605
Biological Process	GO:0032640	tumor necrosis factor production	IMP	J:96018
Biological Process	GO:0032640	tumor necrosis factor production	IMP	J:100140