GO Annotations Graph

• Symbol: Mdm4
• Name: transformed mouse 3T3 cell double minute 4
• ID: MGI:107934

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:170004
Molecular Function	GO:0005515	protein binding	IPI	J:197517
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:72247
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0017053	transcription repressor complex	ISO	J:164563
Biological Process	GO:0003283	atrial septum development	IGI	J:188490
Biological Process	GO:0003181	atrioventricular valve morphogenesis	IGI	J:188490
Biological Process	GO:0003203	endocardial cushion morphogenesis	IGI	J:188490
Biological Process	GO:0003170	heart valve development	IGI	J:188490
Biological Process	GO:0043066	negative regulation of apoptotic process	IEA	J:72247
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	IMP	J:77907
Biological Process	GO:0042177	negative regulation of protein catabolic process	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:88362
Biological Process	GO:0016567	protein ubiquitination	IBA	J:265628
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0051726	regulation of cell cycle	IEA	J:72247
Biological Process	GO:0002027	regulation of heart rate	IGI	J:188490
Biological Process	GO:0003281	ventricular septum development	IGI	J:188490