GO Annotations Graph

• Symbol: Rad21
• Name: RAD21 cohesin complex component
• ID: MGI:108016

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:56371
Molecular Function	GO:0005515	protein binding	IPI	J:185774
Cellular Component	GO:0000785	chromatin	IDA	J:204095
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000775	chromosome, centromeric region	IDA	J:240155
Cellular Component	GO:0008278	cohesin complex	IDA	J:56371
Cellular Component	GO:0008278	cohesin complex	ISO	J:164563
Cellular Component	GO:0008278	cohesin complex	IBA	J:265628
Cellular Component	GO:0008278	cohesin complex	IDA	J:185744
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:211663
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0030496	midbody	ISO	J:164563
Cellular Component	GO:0016363	nuclear matrix	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912355
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912362
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912423
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912449
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912468
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912506
Cellular Component	GO:0005634	nucleus	IDA	J:56371
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0140588	chromatin looping	IMP	J:294078
Biological Process	GO:0007059	chromosome segregation	IEA	J:60000
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	IMP	J:56371
Biological Process	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	IMP	J:56371
Biological Process	GO:0045876	positive regulation of sister chromatid cohesion	ISO	J:164563
Biological Process	GO:0071168	protein localization to chromatin	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:1990414	replication-born double-strand break repair via sister chromatid exchange	IBA	J:265628
Biological Process	GO:0007062	sister chromatid cohesion	IBA	J:265628