GO Annotations Graph

• Symbol: Pkn1
• Name: protein kinase N1
• ID: MGI:108022

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0004698	calcium-dependent protein kinase C activity	IEA	J:72245
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0042393	histone binding	ISO	J:164563
Molecular Function	GO:0042826	histone deacetylase binding	ISO	J:164563
Molecular Function	GO:0035402	histone H3T11 kinase activity	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0050681	nuclear androgen receptor binding	ISO	J:164563
Molecular Function	GO:0030374	nuclear receptor coactivator activity	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:65465
Molecular Function	GO:0004672	protein kinase activity	ISO	J:155856
Molecular Function	GO:0004672	protein kinase activity	IMP	J:85182
Molecular Function	GO:0004697	protein kinase C activity	ISO	J:164563
Molecular Function	GO:0005080	protein kinase C binding	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0031267	small GTPase binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0032154	cleavage furrow	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:85182
Cellular Component	GO:0031410	cytoplasmic vesicle	IDA	J:85182
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0030496	midbody	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0032991	protein-containing complex	ISO	J:193187
Biological Process	GO:0001783	B cell apoptotic process	IMP	J:193187
Biological Process	GO:0001782	B cell homeostasis	IMP	J:193187
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0010631	epithelial cell migration	ISO	J:164563
Biological Process	GO:0006972	hyperosmotic response	IDA	J:85182
Biological Process	GO:0035556	intracellular signal transduction	IBA	J:265628
Biological Process	GO:0030889	negative regulation of B cell proliferation	IMP	J:193187
Biological Process	GO:0006469	negative regulation of protein kinase activity	IMP	J:193187
Biological Process	GO:0001933	negative regulation of protein phosphorylation	IMP	J:193187
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IBA	J:265628
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0043687	post-translational protein modification	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	ISO	J:155856
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:2000145	regulation of cell motility	ISO	J:164563
Biological Process	GO:0002634	regulation of germinal center formation	IMP	J:193187
Biological Process	GO:0002637	regulation of immunoglobulin production	IMP	J:193187
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0003014	renal system process	IMP	J:193187
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0048536	spleen development	IMP	J:193187