GO Annotations Graph

• Symbol: Hyou1
• Name: hypoxia up-regulated 1
• ID: MGI:108030

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0140662	ATP-dependent protein folding chaperone	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0034663	endoplasmic reticulum chaperone complex	IDA	J:217288
Cellular Component	GO:0034663	endoplasmic reticulum chaperone complex	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-3221864
Cellular Component	GO:0005790	smooth endoplasmic reticulum	ISO	J:155856
Biological Process	GO:0071456	cellular response to hypoxia	ISO	J:164563
Biological Process	GO:0071456	cellular response to hypoxia	IBA	J:265628
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:96811
Biological Process	GO:1903382	negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway	IMP	J:117737
Biological Process	GO:1903298	negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway	ISO	J:155856
Biological Process	GO:1903298	negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:1903298	negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway	IBA	J:265628
Biological Process	GO:0031204	post-translational protein targeting to membrane, translocation	IBA	J:265628
Biological Process	GO:0001666	response to hypoxia	ISO	J:155856
Biological Process	GO:0002931	response to ischemia	IDA	J:67962
Biological Process	GO:0002931	response to ischemia	IDA	J:51581