GO Annotations Graph

• Symbol: Rit2
• Name: Ras-like without CAAX 2
• ID: MGI:108054

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005516	calmodulin binding	IPI	J:233584
Molecular Function	GO:0005516	calmodulin binding	IDA	J:36057
Molecular Function	GO:0005516	calmodulin binding	ISO	J:164563
Molecular Function	GO:0005516	calmodulin binding	IBA	J:265628
Molecular Function	GO:0003682	chromatin binding	IGI	J:233585
Molecular Function	GO:0003925	G protein activity	IEA	J:72245
Molecular Function	GO:0019003	GDP binding	IBA	J:265628
Molecular Function	GO:0005525	GTP binding	IDA	J:161040
Molecular Function	GO:0005525	GTP binding	IDA	J:36057
Molecular Function	GO:0005525	GTP binding	IBA	J:265628
Molecular Function	GO:0003924	GTPase activity	IDA	J:161040
Molecular Function	GO:0003924	GTPase activity	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:161040
Molecular Function	GO:0005515	protein binding	IPI	J:233585
Molecular Function	GO:0005515	protein binding	IPI	J:64313
Molecular Function	GO:0030215	semaphorin receptor binding	ISO	J:164563
Cellular Component	GO:0044297	cell body	IDA	J:233565
Cellular Component	GO:0005737	cytoplasm	IDA	J:233585
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0097447	dendritic tree	IDA	J:233565
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:233585
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:36057
Cellular Component	GO:0005886	plasma membrane	IDA	J:233565
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0035556	intracellular signal transduction	ISO	J:164563
Biological Process	GO:0032507	maintenance of protein location in cell	ISO	J:164563
Biological Process	GO:0010977	negative regulation of neuron projection development	IGI	J:233584
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:155856
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:164563
Biological Process	GO:0010976	positive regulation of neuron projection development	IGI	J:76551
Biological Process	GO:0010976	positive regulation of neuron projection development	IDA	J:233584
Biological Process	GO:0010976	positive regulation of neuron projection development	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:233585
Biological Process	GO:0007265	Ras protein signal transduction	IDA	J:76551
Biological Process	GO:0007265	Ras protein signal transduction	IGI	J:76551
Biological Process	GO:0007265	Ras protein signal transduction	IBA	J:265628
Biological Process	GO:0050848	regulation of calcium-mediated signaling	ISO	J:155856
Biological Process	GO:0032489	regulation of Cdc42 protein signal transduction	IDA	J:233584
Biological Process	GO:0030100	regulation of endocytosis	ISO	J:164563
Biological Process	GO:0001932	regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IEA	J:72247