GO Annotations Graph

• Symbol: Ccna2
• Name: cyclin A2
• ID: MGI:108069

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	ISO	J:164563
Molecular Function	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:155178
Molecular Function	GO:0005515	protein binding	IPI	J:245366
Molecular Function	GO:0005515	protein binding	IPI	J:92455
Molecular Function	GO:0005515	protein binding	IPI	J:92455
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	IPI	J:105978
Cellular Component	GO:0097124	cyclin A2-CDK2 complex	ISO	J:164563
Cellular Component	GO:0097124	cyclin A2-CDK2 complex	IBA	J:265628
Cellular Component	GO:0097124	cyclin A2-CDK2 complex	IDA	J:24521
Cellular Component	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:92551
Cellular Component	GO:0005737	cytoplasm	ISO	J:201692
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0001939	female pronucleus	IDA	J:103442
Cellular Component	GO:0001940	male pronucleus	IDA	J:103442
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-8979004
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:92551
Cellular Component	GO:0005634	nucleus	ISO	J:101015
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0044843	cell cycle G1/S phase transition	ISO	J:164563
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0006351	DNA-templated transcription	IMP	J:103442
Biological Process	GO:0006351	DNA-templated transcription	IGI	J:103442
Biological Process	GO:0000086	G2/M transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0044772	mitotic cell cycle phase transition	IBA	J:265628
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IGI	J:103442
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:103442
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	ISO	J:155856
Biological Process	GO:0043687	post-translational protein modification	ISO	J:164563
Biological Process	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	IBA	J:265628
Biological Process	GO:0006275	regulation of DNA replication	ISO	J:164563