Kcnq1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Kcnq1
potassium voltage-gated channel, subfamily Q, member 1
MGI:108083

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005516	calmodulin binding	ISO	J:164563
Molecular Function	GO:0005516	calmodulin binding	IBA	J:265628
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	ISO	J:155856
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	ISO	J:164563
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0015271	outward rectifier potassium channel activity	ISO	J:155856
Molecular Function	GO:0015271	outward rectifier potassium channel activity	ISO	J:164563
Molecular Function	GO:0015271	outward rectifier potassium channel activity	IBA	J:265628
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	ISO	J:164563
Molecular Function	GO:0005267	potassium channel activity	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:258659
Molecular Function	GO:0005515	protein binding	IPI	J:258659
Molecular Function	GO:0034236	protein kinase A catalytic subunit binding	ISO	J:164563
Molecular Function	GO:0034237	protein kinase A regulatory subunit binding	ISO	J:164563
Molecular Function	GO:0008157	protein phosphatase 1 binding	ISO	J:164563
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:164563
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:164563
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Molecular Function	GO:0005249	voltage-gated potassium channel activity	ISO	J:164563
Molecular Function	GO:0005249	voltage-gated potassium channel activity	IDA	J:36442
Molecular Function	GO:0005249	voltage-gated potassium channel activity	ISO	J:164563
Molecular Function	GO:0005249	voltage-gated potassium channel activity	ISO	J:164563
Molecular Function	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	ISO	J:164563
Molecular Function	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	IBA	J:265628
Molecular Function	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	ISO	J:164563
Molecular Function	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	ISO	J:164563
Molecular Function	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	IBA	J:265628
Cellular Component	GO:0045177	apical part of cell	IDA	J:118073
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:258659
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:108905
Cellular Component	GO:1990794	basolateral part of cell	IDA	J:118073
Cellular Component	GO:1990794	basolateral part of cell	IDA	J:106204
Cellular Component	GO:1990794	basolateral part of cell	IDA	J:119156
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IDA	J:121998
Cellular Component	GO:0097546	ciliary base	IDA	J:234526
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:118073
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	ISO	J:155856
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0034702	monoatomic ion channel complex	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	IMP	J:164618
Cellular Component	GO:0043025	neuronal cell body	IDA	J:164618
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0034705	potassium channel complex	IDA	J:148806
Cellular Component	GO:0042383	sarcolemma	ISO	J:155856
Cellular Component	GO:0030133	transport vesicle	IDA	J:194689
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:164563
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:155856
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IBA	J:265628
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IDA	J:258659
Cellular Component	GO:0042589	zymogen granule membrane	ISO	J:155856
Biological Process	GO:0071875	adrenergic receptor signaling pathway	IMP	J:123033
Biological Process	GO:0086014	atrial cardiac muscle cell action potential	ISO	J:164563
Biological Process	GO:0060117	auditory receptor cell development	IMP	J:233544
Biological Process	GO:0061337	cardiac conduction	IMP	J:211437
Biological Process	GO:0060048	cardiac muscle contraction	ISO	J:164563
Biological Process	GO:0060048	cardiac muscle contraction	IMP	J:124275
Biological Process	GO:0071320	cellular response to cAMP	ISO	J:164563
Biological Process	GO:0071872	cellular response to epinephrine stimulus	IMP	J:123033
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	ISO	J:164563
Biological Process	GO:0055064	chloride ion homeostasis	IMP	J:104389
Biological Process	GO:0072359	circulatory system development	IMP	J:100283
Biological Process	GO:0090102	cochlea development	IMP	J:110797
Biological Process	GO:0035934	corticosterone secretion	IMP	J:124275
Biological Process	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	IMP	J:110797
Biological Process	GO:0030218	erythrocyte differentiation	IMP	J:104389
Biological Process	GO:0001696	gastric acid secretion	IMP	J:94410
Biological Process	GO:0001696	gastric acid secretion	IMP	J:176794
Biological Process	GO:0001696	gastric acid secretion	IMP	J:104389
Biological Process	GO:0001698	gastrin-induced gastric acid secretion	IMP	J:124275
Biological Process	GO:0010467	gene expression	IMP	J:94410
Biological Process	GO:0010467	gene expression	IMP	J:124275
Biological Process	GO:0010467	gene expression	IMP	J:212747
Biological Process	GO:0006006	glucose metabolic process	IMP	J:148694
Biological Process	GO:0007507	heart development	IMP	J:93197
Biological Process	GO:0048839	inner ear development	IMP	J:66428
Biological Process	GO:0048839	inner ear development	IMP	J:93197
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:67873
Biological Process	GO:0050892	intestinal absorption	ISO	J:155856
Biological Process	GO:0030644	intracellular chloride ion homeostasis	IMP	J:119156
Biological Process	GO:0030644	intracellular chloride ion homeostasis	IDA	J:119156
Biological Process	GO:0015705	iodide transport	IMP	J:187467
Biological Process	GO:0086009	membrane repolarization	IMP	J:104389
Biological Process	GO:0086011	membrane repolarization during action potential	ISO	J:164563
Biological Process	GO:0086011	membrane repolarization during action potential	IMP	J:164618
Biological Process	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential	ISO	J:164563
Biological Process	GO:0086013	membrane repolarization during cardiac muscle cell action potential	ISO	J:164563
Biological Process	GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential	ISO	J:164563
Biological Process	GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential	IBA	J:265628
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:1902260	negative regulation of delayed rectifier potassium channel activity	ISO	J:164563
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:92776
Biological Process	GO:0046676	negative regulation of insulin secretion	ISO	J:155856
Biological Process	GO:1903817	negative regulation of voltage-gated potassium channel activity	ISO	J:164563
Biological Process	GO:1905515	non-motile cilium assembly	IDA	J:234526
Biological Process	GO:1905515	non-motile cilium assembly	IMP	J:234526
Biological Process	GO:0060452	positive regulation of cardiac muscle contraction	ISO	J:164563
Biological Process	GO:0060454	positive regulation of gastric acid secretion	ISO	J:155856
Biological Process	GO:0010460	positive regulation of heart rate	ISO	J:164563
Biological Process	GO:1901381	positive regulation of potassium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0097623	potassium ion export across plasma membrane	ISO	J:164563
Biological Process	GO:0097623	potassium ion export across plasma membrane	IBA	J:265628
Biological Process	GO:0055075	potassium ion homeostasis	IMP	J:104389
Biological Process	GO:1990573	potassium ion import across plasma membrane	IMP	J:148694
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0071805	potassium ion transmembrane transport	IMP	J:119156
Biological Process	GO:0071805	potassium ion transmembrane transport	IMP	J:176794
Biological Process	GO:0071805	potassium ion transmembrane transport	IDA	J:119156
Biological Process	GO:0006813	potassium ion transport	ISO	J:155856
Biological Process	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization	ISO	J:164563
Biological Process	GO:0008217	regulation of blood pressure	IMP	J:124275
Biological Process	GO:0060453	regulation of gastric acid secretion	IMP	J:104389
Biological Process	GO:0060453	regulation of gastric acid secretion	IMP	J:176794
Biological Process	GO:0006349	regulation of gene expression by genomic imprinting	IMP	J:92776
Biological Process	GO:0006349	regulation of gene expression by genomic imprinting	IMP	J:79882
Biological Process	GO:0002027	regulation of heart rate	IMP	J:164618
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	ISO	J:164563
Biological Process	GO:0042391	regulation of membrane potential	ISO	J:155856
Biological Process	GO:0060306	regulation of membrane repolarization	ISO	J:164563
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:0032409	regulation of transporter activity	IMP	J:258659
Biological Process	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	ISO	J:164563
Biological Process	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	IMP	J:67873
Biological Process	GO:1905150	regulation of voltage-gated sodium channel activity	IMP	J:211437
Biological Process	GO:0070293	renal absorption	IMP	J:104389
Biological Process	GO:0070294	renal sodium ion absorption	IMP	J:104389
Biological Process	GO:0072347	response to anesthetic	ISO	J:155856
Biological Process	GO:0071871	response to epinephrine	IMP	J:123819
Biological Process	GO:0071871	response to epinephrine	IMP	J:100283
Biological Process	GO:0032868	response to insulin	IMP	J:148694
Biological Process	GO:0035094	response to nicotine	IMP	J:123819
Biological Process	GO:0007622	rhythmic behavior	IMP	J:110797
Biological Process	GO:0007605	sensory perception of sound	IMP	J:93197
Biological Process	GO:0007605	sensory perception of sound	IMP	J:233544
Biological Process	GO:0007605	sensory perception of sound	IMP	J:67873
Biological Process	GO:0035176	social behavior	IMP	J:93197
Biological Process	GO:0006814	sodium ion transport	IMP	J:119156
Biological Process	GO:0006814	sodium ion transport	IDA	J:119156
Biological Process	GO:0062094	stomach development	IMP	J:94410
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0086005	ventricular cardiac muscle cell action potential	ISO	J:164563

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