GO Annotations Graph

• Symbol: Gab1
• Name: growth factor receptor bound protein 2-associated protein 1
• ID: MGI:108088

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:206901
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0005515	protein binding	IPI	J:200336
Molecular Function	GO:0005515	protein binding	IPI	J:128861
Molecular Function	GO:0005515	protein binding	IPI	J:248455
Molecular Function	GO:0005515	protein binding	IPI	J:248455
Molecular Function	GO:0035591	signaling adaptor activity	IBA	J:265628
Molecular Function	GO:0035591	signaling adaptor activity	IDA	J:91609
Molecular Function	GO:0035591	signaling adaptor activity	IMP	J:125303
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:98531
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9031076
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9031553
Biological Process	GO:0031532	actin cytoskeleton reorganization	ISO	J:164563
Biological Process	GO:0001525	angiogenesis	ISO	J:164563
Biological Process	GO:0035924	cellular response to vascular endothelial growth factor stimulus	IDA	J:248455
Biological Process	GO:0090668	endothelial cell chemotaxis to vascular endothelial growth factor	ISO	J:164563
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	IMP	J:125303
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	IMP	J:61790
Biological Process	GO:0008544	epidermis development	IMP	J:61790
Biological Process	GO:0008544	epidermis development	IMP	J:61790
Biological Process	GO:0007507	heart development	IMP	J:61790
Biological Process	GO:0070102	interleukin-6-mediated signaling pathway	IMP	J:61790
Biological Process	GO:0060711	labyrinthine layer development	IMP	J:61790
Biological Process	GO:0000165	MAPK cascade	IMP	J:61790
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	IMP	J:61790
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0038089	positive regulation of cell migration by vascular endothelial growth factor signaling pathway	IDA	J:248455
Biological Process	GO:0043406	positive regulation of MAP kinase activity	IMP	J:83953
Biological Process	GO:0043410	positive regulation of MAPK cascade	IDA	J:77668
Biological Process	GO:0043410	positive regulation of MAPK cascade	IMP	J:61790
Biological Process	GO:0030334	regulation of cell migration	IGI	J:100909
Biological Process	GO:0035728	response to hepatocyte growth factor	ISO	J:155856
Biological Process	GO:0006979	response to oxidative stress	IDA	J:83953
Biological Process	GO:0007165	signal transduction	IBA	J:265628
Biological Process	GO:0007165	signal transduction	IDA	J:77668
Biological Process	GO:0038084	vascular endothelial growth factor signaling pathway	ISO	J:164563