GO Annotations Graph

• Symbol: Dhx9
• Name: DExH-box helicase 9
• ID: MGI:108177

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043138	3'-5' DNA helicase activity	ISO	J:164563
Molecular Function	GO:0043138	3'-5' DNA helicase activity	IBA	J:265628
Molecular Function	GO:0033679	3'-5' DNA/RNA helicase activity	ISO	J:164563
Molecular Function	GO:0034458	3'-5' RNA helicase activity	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:164563
Molecular Function	GO:0016887	ATP hydrolysis activity	IBA	J:265628
Molecular Function	GO:0031490	chromatin DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003678	DNA helicase activity	ISO	J:164563
Molecular Function	GO:0003688	DNA replication origin binding	ISO	J:164563
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003725	double-stranded RNA binding	ISO	J:164563
Molecular Function	GO:0004386	helicase activity	IEA	J:72247
Molecular Function	GO:0004386	helicase activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0061676	importin-alpha family protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0003729	mRNA binding	ISO	J:164563
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0047429	nucleoside triphosphate diphosphatase activity	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:1905538	polysome binding	ISO	J:164563
Molecular Function	GO:1990841	promoter-specific chromatin binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:130327
Molecular Function	GO:0005515	protein binding	IPI	J:243505
Molecular Function	GO:0005515	protein binding	IPI	J:185950
Molecular Function	GO:0005515	protein binding	IPI	J:185950
Molecular Function	GO:0001069	regulatory region RNA binding	IDA	J:243505
Molecular Function	GO:0001069	regulatory region RNA binding	ISO	J:164563
Molecular Function	GO:1905172	RISC complex binding	ISO	J:164563
Molecular Function	GO:0003723	RNA binding	ISO	J:164563
Molecular Function	GO:0003723	RNA binding	IBA	J:265628
Molecular Function	GO:0003724	RNA helicase activity	ISO	J:164563
Molecular Function	GO:0003724	RNA helicase activity	IBA	J:265628
Molecular Function	GO:0070063	RNA polymerase binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000993	RNA polymerase II complex binding	ISO	J:164563
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0035613	RNA stem-loop binding	ISO	J:164563
Molecular Function	GO:1990825	sequence-specific mRNA binding	ISO	J:164563
Molecular Function	GO:1990518	single-stranded 3'-5' DNA helicase activity	ISO	J:164563
Molecular Function	GO:0003697	single-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003727	single-stranded RNA binding	ISO	J:164563
Molecular Function	GO:0035197	siRNA binding	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0003712	transcription coregulator activity	ISO	J:164563
Molecular Function	GO:0045142	triplex DNA binding	ISO	J:164563
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0070937	CRD-mediated mRNA stability complex	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005622	intracellular anatomical structure	IBA	J:265628
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0097165	nuclear stress granule	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	IBA	J:265628
Cellular Component	GO:0005730	nucleolus	IDA	J:87744
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005726	perichromatin fibrils	ISO	J:164563
Cellular Component	GO:0042788	polysomal ribosome	ISO	J:164563
Cellular Component	GO:0005844	polysome	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:164563
Cellular Component	GO:1990904	ribonucleoprotein complex	IBA	J:265628
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:142821
Cellular Component	GO:0016442	RISC complex	ISO	J:164563
Cellular Component	GO:0070578	RISC-loading complex	ISO	J:164563
Biological Process	GO:0000380	alternative mRNA splicing, via spliceosome	ISO	J:164563
Biological Process	GO:0071360	cellular response to exogenous dsRNA	ISO	J:164563
Biological Process	GO:0034605	cellular response to heat	IDA	J:142548
Biological Process	GO:0071356	cellular response to tumor necrosis factor	ISO	J:164563
Biological Process	GO:0007623	circadian rhythm	IMP	J:185950
Biological Process	GO:0070934	CRD-mediated mRNA stabilization	ISO	J:164563
Biological Process	GO:0032508	DNA duplex unwinding	ISO	J:164563
Biological Process	GO:0006353	DNA-templated transcription termination	IEA	J:60000
Biological Process	GO:0039695	DNA-templated viral transcription	ISO	J:164563
Biological Process	GO:0044806	G-quadruplex DNA unwinding	ISO	J:164563
Biological Process	GO:0098795	global gene silencing by mRNA cleavage	ISO	J:164563
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0006954	inflammatory response	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:0051028	mRNA transport	IEA	J:60000
Biological Process	GO:1900152	negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	ISO	J:164563
Biological Process	GO:2000767	positive regulation of cytoplasmic translation	ISO	J:164563
Biological Process	GO:0045739	positive regulation of DNA repair	ISO	J:164563
Biological Process	GO:0045740	positive regulation of DNA replication	ISO	J:164563
Biological Process	GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	ISO	J:164563
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	ISO	J:164563
Biological Process	GO:0050729	positive regulation of inflammatory response	IMP	J:243487
Biological Process	GO:0045089	positive regulation of innate immune response	IMP	J:243487
Biological Process	GO:0032727	positive regulation of interferon-alpha production	ISO	J:164563
Biological Process	GO:0032728	positive regulation of interferon-beta production	ISO	J:164563
Biological Process	GO:0032741	positive regulation of interleukin-18 production	IMP	J:243487
Biological Process	GO:0032755	positive regulation of interleukin-6 production	ISO	J:164563
Biological Process	GO:2000637	positive regulation of miRNA-mediated gene silencing	ISO	J:164563
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:1905698	positive regulation of polysome binding	ISO	J:164563
Biological Process	GO:0060760	positive regulation of response to cytokine stimulus	ISO	J:164563
Biological Process	GO:0046833	positive regulation of RNA export from nucleus	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ISO	J:164563
Biological Process	GO:0050434	positive regulation of viral transcription	ISO	J:164563
Biological Process	GO:1904973	positive regulation of viral translation	ISO	J:164563
Biological Process	GO:1903608	protein localization to cytoplasmic stress granule	ISO	J:164563
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0070269	pyroptosis	IMP	J:243487
Biological Process	GO:2000765	regulation of cytoplasmic translation	ISO	J:164563
Biological Process	GO:0050691	regulation of defense response to virus by host	IMP	J:243487
Biological Process	GO:0050684	regulation of mRNA processing	ISO	J:164563
Biological Process	GO:0050684	regulation of mRNA processing	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006417	regulation of translation	IEA	J:60000
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:0070922	RISC complex assembly	ISO	J:164563
Biological Process	GO:0010501	RNA secondary structure unwinding	ISO	J:164563
Biological Process	GO:0008380	RNA splicing	IEA	J:60000
Biological Process	GO:0031047	RNA-mediated gene silencing	IEA	J:60000