GO Annotations Graph

• Symbol: Rgs4
• Name: regulator of G-protein signaling 4
• ID: MGI:108409

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001965	G-protein alpha-subunit binding	ISO	J:155856
Molecular Function	GO:0005096	GTPase activator activity	ISO	J:155856
Molecular Function	GO:0005096	GTPase activator activity	TAS	J:69278
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	TAS	J:69278
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	TAS	J:69278
Biological Process	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	ISO	J:155856
Biological Process	GO:0060160	negative regulation of dopamine receptor signaling pathway	ISO	J:155856
Biological Process	GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:1900924	negative regulation of glycine import across plasma membrane	ISO	J:155856
Biological Process	GO:1901380	negative regulation of potassium ion transmembrane transport	ISO	J:155856
Biological Process	GO:0009968	negative regulation of signal transduction	IEA	J:60000
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	ISO	J:155856
Biological Process	GO:0043547	positive regulation of GTPase activity	ISO	J:155856
Biological Process	GO:0010460	positive regulation of heart rate	ISO	J:155856
Biological Process	GO:0110053	regulation of actin filament organization	ISO	J:155856
Biological Process	GO:0051924	regulation of calcium ion transport	ISO	J:155856
Biological Process	GO:1901379	regulation of potassium ion transmembrane transport	ISO	J:155856