GO Annotations Graph

• Symbol: Pde1c
• Name: phosphodiesterase 1C
• ID: MGI:108413

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	IDA	J:35869
Molecular Function	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	ISO	J:164563
Molecular Function	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	IDA	J:35869
Molecular Function	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	ISO	J:164563
Molecular Function	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	IEA	J:72245
Molecular Function	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	IEA	J:72247
Molecular Function	GO:0005516	calmodulin binding	IEA	J:60000
Molecular Function	GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	IBA	J:265628
Molecular Function	GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	ISO	J:37553
Molecular Function	GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	ISO	J:155856
Molecular Function	GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	ISO	J:164563
Molecular Function	GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	ISO	J:37553
Molecular Function	GO:0030552	cAMP binding	ISO	J:155856
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008081	phosphoric diester hydrolase activity	IEA	J:72247
Cellular Component	GO:0005929	cilium	IDA	J:150514
Cellular Component	GO:0005764	lysosome	IDA	J:322385
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	IBA	J:265628
Biological Process	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	ISO	J:155856
Biological Process	GO:0051592	response to calcium ion	ISO	J:37553
Biological Process	GO:0007608	sensory perception of smell	IGI	J:150514
Biological Process	GO:0007608	sensory perception of smell	IMP	J:150514
Biological Process	GO:0007165	signal transduction	IEA	J:72247