GO Annotations Graph

• Symbol: Lpar1
• Name: lysophosphatidic acid receptor 1
• ID: MGI:108429

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0001965	G-protein alpha-subunit binding	ISO	J:155856
Molecular Function	GO:0035727	lysophosphatidic acid binding	ISO	J:164563
Molecular Function	GO:0070915	lysophosphatidic acid receptor activity	IDA	J:222685
Molecular Function	GO:0070915	lysophosphatidic acid receptor activity	IDA	J:36844
Molecular Function	GO:0070915	lysophosphatidic acid receptor activity	IDA	J:222688
Molecular Function	GO:0070915	lysophosphatidic acid receptor activity	ISO	J:164563
Molecular Function	GO:0070915	lysophosphatidic acid receptor activity	IBA	J:265628
Molecular Function	GO:0030165	PDZ domain binding	IPI	J:99931
Molecular Function	GO:0030165	PDZ domain binding	IPI	J:99931
Molecular Function	GO:0005543	phospholipid binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:99931
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0043198	dendritic shaft	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0030139	endocytic vesicle	ISO	J:164563
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0098982	GABA-ergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:222688
Cellular Component	GO:0005886	plasma membrane	IDA	J:36844
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Biological Process	GO:0007202	activation of phospholipase C activity	ISO	J:164563
Biological Process	GO:0007202	activation of phospholipase C activity	IDA	J:222685
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	IDA	J:222685
Biological Process	GO:0032060	bleb assembly	IGI	J:120291
Biological Process	GO:0060326	cell chemotaxis	ISO	J:164563
Biological Process	GO:1904566	cellular response to 1-oleoyl-sn-glycerol 3-phosphate	ISO	J:155856
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IDA	J:222688
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IDA	J:36844
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IDA	J:99931
Biological Process	GO:0043951	negative regulation of cAMP-mediated signaling	ISO	J:155856
Biological Process	GO:0010977	negative regulation of neuron projection development	IMP	J:222688
Biological Process	GO:0010977	negative regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0010977	negative regulation of neuron projection development	IDA	J:222685
Biological Process	GO:0022008	neurogenesis	IBA	J:265628
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0010942	positive regulation of cell death	ISO	J:155856
Biological Process	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	ISO	J:164563
Biological Process	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	ISO	J:155856
Biological Process	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	IBA	J:265628
Biological Process	GO:0060999	positive regulation of dendritic spine development	ISO	J:155856
Biological Process	GO:0043410	positive regulation of MAPK cascade	IDA	J:222685
Biological Process	GO:0043410	positive regulation of MAPK cascade	IDA	J:99931
Biological Process	GO:0035025	positive regulation of Rho protein signal transduction	IMP	J:222688
Biological Process	GO:0035025	positive regulation of Rho protein signal transduction	IDA	J:222685
Biological Process	GO:0035025	positive regulation of Rho protein signal transduction	IDA	J:99931
Biological Process	GO:0071673	positive regulation of smooth muscle cell chemotaxis	ISO	J:155856
Biological Process	GO:0051496	positive regulation of stress fiber assembly	IDA	J:222688
Biological Process	GO:0008360	regulation of cell shape	IDA	J:36844
Biological Process	GO:0008360	regulation of cell shape	IDA	J:222685
Biological Process	GO:0008360	regulation of cell shape	IMP	J:222688
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	ISO	J:155856
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IEA	J:60000