GO Annotations Graph

• Symbol: Adcyap1r1
• Name: adenylate cyclase activating polypeptide 1 receptor 1
• ID: MGI:108449

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008179	adenylate cyclase binding	ISO	J:155856
Molecular Function	GO:0008528	G protein-coupled peptide receptor activity	IBA	J:265628
Molecular Function	GO:0004930	G protein-coupled receptor activity	TAS	J:49214
Molecular Function	GO:0042923	neuropeptide binding	ISO	J:155856
Molecular Function	GO:0017046	peptide hormone binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:180398
Molecular Function	GO:0031267	small GTPase binding	ISO	J:155856
Molecular Function	GO:0004888	transmembrane signaling receptor activity	IEA	J:72247
Molecular Function	GO:0004999	vasoactive intestinal polypeptide receptor activity	TAS	J:49214
Cellular Component	GO:0005923	bicellular tight junction	ISO	J:155856
Cellular Component	GO:0005901	caveola	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005768	endosome	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Cellular Component	GO:0005791	rough endoplasmic reticulum	ISO	J:155856
Biological Process	GO:0007202	activation of phospholipase C activity	ISO	J:155856
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0019933	cAMP-mediated signaling	ISO	J:155856
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0007166	cell surface receptor signaling pathway	IEA	J:72247
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	TAS	J:49214
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:155856
Biological Process	GO:0010524	positive regulation of calcium ion transport into cytosol	ISO	J:155856
Biological Process	GO:0043950	positive regulation of cAMP-mediated signaling	ISO	J:155856
Biological Process	GO:0060732	positive regulation of inositol phosphate biosynthetic process	ISO	J:155856
Biological Process	GO:0051057	positive regulation of small GTPase mediated signal transduction	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0007283	spermatogenesis	IEA	J:60000