GO Annotations Graph

• Symbol: Nbr1
• Name: NBR1, autophagy cargo receptor
• ID: MGI:108498

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0051019	mitogen-activated protein kinase binding	IDA	J:162412
Molecular Function	GO:0005515	protein binding	IPI	J:146216
Molecular Function	GO:0043130	ubiquitin binding	ISO	J:164563
Molecular Function	GO:0043130	ubiquitin binding	IBA	J:265628
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005776	autophagosome	IDA	J:162412
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9666410
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005770	late endosome	IDA	J:146216
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0005758	mitochondrial intermembrane space	IDA	J:215645
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005778	peroxisomal membrane	TAS	Reactome:R-MMU-9666410
Cellular Component	GO:0000407	phagophore assembly site	IBA	J:265628
Cellular Component	GO:0000407	phagophore assembly site	IDA	J:167845
Cellular Component	GO:0043235	receptor complex	ISO	J:164563
Biological Process	GO:0016236	macroautophagy	ISO	J:164563
Biological Process	GO:0016236	macroautophagy	IBA	J:265628
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	IMP	J:162412
Biological Process	GO:0030500	regulation of bone mineralization	IMP	J:162412
Biological Process	GO:0032872	regulation of stress-activated MAPK cascade	IMP	J:162412