GO Annotations Graph

• Symbol: Fzd7
• Name: frizzled class receptor 7
• ID: MGI:108570

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005109	frizzled binding	ISO	J:164563
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:164563
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:200324
Molecular Function	GO:0005515	protein binding	IPI	J:163736
Molecular Function	GO:0005515	protein binding	IPI	J:130925
Molecular Function	GO:0004888	transmembrane signaling receptor activity	IEA	J:72247
Molecular Function	GO:0042813	Wnt receptor activity	ISO	J:164563
Molecular Function	GO:0042813	Wnt receptor activity	IBA	J:265628
Molecular Function	GO:0042813	Wnt receptor activity	IMP	J:149821
Molecular Function	GO:0017147	Wnt-protein binding	ISO	J:164563
Molecular Function	GO:0017147	Wnt-protein binding	IBA	J:265628
Molecular Function	GO:0017147	Wnt-protein binding	IPI	J:149821
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	IMP	J:130925
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-NUL-517516
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:149821
Cellular Component	GO:0005886	plasma membrane	IDA	J:130925
Cellular Component	GO:0055038	recycling endosome membrane	ISO	J:164563
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:227384
Biological Process	GO:0060070	canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0060070	canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0060070	canonical Wnt signaling pathway	IMP	J:67003
Biological Process	GO:0007166	cell surface receptor signaling pathway	IEA	J:72247
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0060231	mesenchymal to epithelial transition	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:2000726	negative regulation of cardiac muscle cell differentiation	ISO	J:164563
Biological Process	GO:0010812	negative regulation of cell-substrate adhesion	IMP	J:130925
Biological Process	GO:0010812	negative regulation of cell-substrate adhesion	ISO	J:164563
Biological Process	GO:0042666	negative regulation of ectodermal cell fate specification	ISO	J:164563
Biological Process	GO:0035567	non-canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0035567	non-canonical Wnt signaling pathway	IGI	J:149821
Biological Process	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing	ISO	J:164563
Biological Process	GO:0042327	positive regulation of phosphorylation	ISO	J:164563
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	IMP	J:149821
Biological Process	GO:0048103	somatic stem cell division	IMP	J:149821
Biological Process	GO:0019827	stem cell population maintenance	ISO	J:164563
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	IMP	J:130925
Biological Process	GO:0033077	T cell differentiation in thymus	IMP	J:67003
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:72247