GO Annotations Graph

• Symbol: Vegfc
• Name: vascular endothelial growth factor C
• ID: MGI:109124

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042056	chemoattractant activity	ISO	J:164563
Molecular Function	GO:0042056	chemoattractant activity	IBA	J:265628
Molecular Function	GO:0008083	growth factor activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:245358
Molecular Function	GO:0043185	vascular endothelial growth factor receptor 3 binding	ISO	J:164563
Molecular Function	GO:0043185	vascular endothelial growth factor receptor 3 binding	ISO	J:155856
Molecular Function	GO:0043185	vascular endothelial growth factor receptor 3 binding	IBA	J:265628
Molecular Function	GO:0043185	vascular endothelial growth factor receptor 3 binding	IPI	J:37681
Molecular Function	GO:0043185	vascular endothelial growth factor receptor 3 binding	IPI	J:46616
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	IDA	J:209725
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:46616
Cellular Component	GO:0016020	membrane	IEA	J:72247
Biological Process	GO:0001525	angiogenesis	ISO	J:155856
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:87394
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0008283	cell population proliferation	IMP	J:107096
Biological Process	GO:0008283	cell population proliferation	IMP	J:107096
Biological Process	GO:0008283	cell population proliferation	IMP	J:107096
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0014009	glial cell proliferation	IMP	J:107096
Biological Process	GO:0050930	induction of positive chemotaxis	ISO	J:164563
Biological Process	GO:0050930	induction of positive chemotaxis	IBA	J:265628
Biological Process	GO:0016331	morphogenesis of embryonic epithelium	IMP	J:87394
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045776	negative regulation of blood pressure	ISO	J:155856
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	IDA	J:281213
Biological Process	GO:0045766	positive regulation of angiogenesis	IDA	J:209725
Biological Process	GO:0045766	positive regulation of angiogenesis	IBA	J:265628
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	ISO	J:155856
Biological Process	GO:0051781	positive regulation of cell division	IEA	J:60000
Biological Process	GO:0030335	positive regulation of cell migration	IDA	J:281213
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:107096
Biological Process	GO:0008284	positive regulation of cell population proliferation	IGI	J:46616
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:73065
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	IBA	J:265628
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	ISO	J:155856
Biological Process	GO:0060252	positive regulation of glial cell proliferation	IMP	J:107096
Biological Process	GO:1901492	positive regulation of lymphangiogenesis	IDA	J:209725
Biological Process	GO:1901492	positive regulation of lymphangiogenesis	IDA	J:158639
Biological Process	GO:0060754	positive regulation of mast cell chemotaxis	ISO	J:164563
Biological Process	GO:0060754	positive regulation of mast cell chemotaxis	IBA	J:265628
Biological Process	GO:1902462	positive regulation of mesenchymal stem cell proliferation	IDA	J:281213
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	ISO	J:73065
Biological Process	GO:0031954	positive regulation of protein autophosphorylation	ISO	J:155856
Biological Process	GO:0045860	positive regulation of protein kinase activity	IDA	J:281213
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IBA	J:265628
Biological Process	GO:0050714	positive regulation of protein secretion	ISO	J:155856
Biological Process	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	ISO	J:155856
Biological Process	GO:0001666	response to hypoxia	IBA	J:265628
Biological Process	GO:0002040	sprouting angiogenesis	IBA	J:265628
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	IDA	J:209725
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	IBA	J:265628
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	IGI	J:46616
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	IDA	J:37681
Biological Process	GO:0038084	vascular endothelial growth factor signaling pathway	IBA	J:265628