GO Annotations Graph

• Symbol: Ltbp1
• Name: latent transforming growth factor beta binding protein 1
• ID: MGI:109151

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265607
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265604
Molecular Function	GO:0019838	growth factor binding	IEA	J:60000
Molecular Function	GO:0050436	microfibril binding	ISO	J:164563
Molecular Function	GO:0050436	microfibril binding	IBA	J:265628
Molecular Function	GO:0050431	transforming growth factor beta binding	ISO	J:164563
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:164563
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0031012	extracellular matrix	ISO	J:164563
Cellular Component	GO:0031012	extracellular matrix	IDA	J:37693
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0038045	large latent transforming growth factor-beta complex	ISO	J:155856
Cellular Component	GO:0001527	microfibril	ISO	J:164563
Cellular Component	GO:0001527	microfibril	IDA	J:151111
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0035904	aorta development	IMP	J:222159
Biological Process	GO:0060976	coronary vasculature development	IMP	J:222159
Biological Process	GO:0032967	positive regulation of collagen biosynthetic process	ISO	J:155856
Biological Process	GO:1901388	regulation of transforming growth factor beta activation	ISO	J:164563
Biological Process	GO:0035583	sequestering of TGFbeta in extracellular matrix	ISO	J:164563
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	TAS	J:24946
Biological Process	GO:0003281	ventricular septum development	IMP	J:222159