GO Annotations Graph

• Symbol: Mnx1
• Name: motor neuron and pancreas homeobox 1
• ID: MGI:109160

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA	J:72247
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:155856
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	IBA	J:265628
Cellular Component	GO:0000785	chromatin	IDA	J:328860
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:116994
Cellular Component	GO:0005634	nucleus	IDA	J:198828
Biological Process	GO:0048667	cell morphogenesis involved in neuron differentiation	IMP	J:57340
Biological Process	GO:0048667	cell morphogenesis involved in neuron differentiation	IMP	J:57340
Biological Process	GO:0048667	cell morphogenesis involved in neuron differentiation	IMP	J:57340
Biological Process	GO:0007417	central nervous system development	IBA	J:265628
Biological Process	GO:0021953	central nervous system neuron differentiation	IMP	J:57340
Biological Process	GO:0021953	central nervous system neuron differentiation	IMP	J:57340
Biological Process	GO:0021953	central nervous system neuron differentiation	IMP	J:57340
Biological Process	GO:0060539	diaphragm development	IMP	J:57340
Biological Process	GO:0060539	diaphragm development	IMP	J:57340
Biological Process	GO:0060539	diaphragm development	IMP	J:57340
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	IDA	J:138713
Biological Process	GO:0031018	endocrine pancreas development	IBA	J:265628
Biological Process	GO:0031018	endocrine pancreas development	IMP	J:57317
Biological Process	GO:0008045	motor neuron axon guidance	IMP	J:57340
Biological Process	GO:0008045	motor neuron axon guidance	IMP	J:57340
Biological Process	GO:0008045	motor neuron axon guidance	IMP	J:57340
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:328860
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0021675	nerve development	IMP	J:69623
Biological Process	GO:0030182	neuron differentiation	IMP	J:69623
Biological Process	GO:0001764	neuron migration	IMP	J:57340
Biological Process	GO:0001764	neuron migration	IMP	J:57340
Biological Process	GO:0001764	neuron migration	IMP	J:57340
Biological Process	GO:0048812	neuron projection morphogenesis	IBA	J:265628
Biological Process	GO:0048812	neuron projection morphogenesis	IMP	J:57340
Biological Process	GO:0048812	neuron projection morphogenesis	IMP	J:57340
Biological Process	GO:0048812	neuron projection morphogenesis	IMP	J:57340
Biological Process	GO:0031016	pancreas development	IMP	J:57317
Biological Process	GO:0009791	post-embryonic development	IMP	J:57340
Biological Process	GO:0009791	post-embryonic development	IMP	J:57340
Biological Process	GO:0009791	post-embryonic development	IMP	J:57340
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0060541	respiratory system development	IMP	J:57340
Biological Process	GO:0060541	respiratory system development	IMP	J:57340
Biological Process	GO:0060541	respiratory system development	IMP	J:57340
Biological Process	GO:0021520	spinal cord motor neuron cell fate specification	IMP	J:328860
Biological Process	GO:0021520	spinal cord motor neuron cell fate specification	IBA	J:265628
Biological Process	GO:0021520	spinal cord motor neuron cell fate specification	IMP	J:57340
Biological Process	GO:0021520	spinal cord motor neuron cell fate specification	IMP	J:57340
Biological Process	GO:0021520	spinal cord motor neuron cell fate specification	IMP	J:57340