GO Annotations Graph

• Symbol: Cd59a
• Name: CD59a antigen
• ID: MGI:109177

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001848	complement binding	ISO	J:155856
Molecular Function	GO:0001848	complement binding	IBA	J:265628
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:70846
Cellular Component	GO:0043218	compact myelin	ISO	J:155856
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:147119
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:145047
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:70846
Cellular Component	GO:0042383	sarcolemma	ISO	J:155856
Biological Process	GO:0001971	negative regulation of activation of membrane attack complex	ISO	J:155856
Biological Process	GO:0001971	negative regulation of activation of membrane attack complex	IMP	J:143638
Biological Process	GO:0001971	negative regulation of activation of membrane attack complex	IBA	J:265628
Biological Process	GO:0001971	negative regulation of activation of membrane attack complex	IDA	J:70846
Biological Process	GO:0016525	negative regulation of angiogenesis	IMP	J:143638
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0045916	negative regulation of complement activation	IDA	J:143638
Biological Process	GO:1903660	negative regulation of complement-dependent cytotoxicity	ISO	J:155856
Biological Process	GO:0090272	negative regulation of fibroblast growth factor production	IDA	J:143638
Biological Process	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	IMP	J:143638
Biological Process	GO:0042102	positive regulation of T cell proliferation	ISO	J:155856
Biological Process	GO:0030449	regulation of complement activation	ISO	J:218542
Biological Process	GO:1903659	regulation of complement-dependent cytotoxicity	ISO	J:218542