GO Annotations Graph

• Symbol: Ccn3
• Name: cellular communication network factor 3
• ID: MGI:109185

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008083	growth factor activity	IEA	J:60000
Molecular Function	GO:0008201	heparin binding	IBA	J:265628
Molecular Function	GO:0005178	integrin binding	ISO	J:164563
Molecular Function	GO:0005178	integrin binding	IBA	J:265628
Molecular Function	GO:0005112	Notch binding	ISO	J:164563
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0031012	extracellular matrix	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005921	gap junction	ISO	J:155856
Cellular Component	GO:0005921	gap junction	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Biological Process	GO:0001525	angiogenesis	ISO	J:164563
Biological Process	GO:1990523	bone regeneration	IMP	J:199662
Biological Process	GO:0007155	cell adhesion	IBA	J:265628
Biological Process	GO:0033627	cell adhesion mediated by integrin	ISO	J:164563
Biological Process	GO:0060326	cell chemotaxis	ISO	J:164563
Biological Process	GO:0002062	chondrocyte differentiation	ISO	J:155856
Biological Process	GO:0002062	chondrocyte differentiation	ISO	J:164563
Biological Process	GO:0035767	endothelial cell chemotaxis	ISO	J:164563
Biological Process	GO:0071603	endothelial cell-cell adhesion	ISO	J:164563
Biological Process	GO:0010761	fibroblast migration	ISO	J:164563
Biological Process	GO:0061484	hematopoietic stem cell homeostasis	ISO	J:164563
Biological Process	GO:0060548	negative regulation of cell death	IBA	J:265628
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:164563
Biological Process	GO:1902731	negative regulation of chondrocyte proliferation	ISO	J:164563
Biological Process	GO:0050728	negative regulation of inflammatory response	IMP	J:215090
Biological Process	GO:0046676	negative regulation of insulin secretion	IDA	J:202162
Biological Process	GO:0090027	negative regulation of monocyte chemotaxis	ISO	J:164563
Biological Process	GO:0010832	negative regulation of myotube differentiation	ISO	J:164563
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:1904057	negative regulation of sensory perception of pain	ISO	J:155856
Biological Process	GO:0060392	negative regulation of SMAD protein signal transduction	IMP	J:199662
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	ISO	J:164563
Biological Process	GO:0010468	regulation of gene expression	ISO	J:155442
Biological Process	GO:0007165	signal transduction	IBA	J:265628
Biological Process	GO:0014909	smooth muscle cell migration	ISO	J:164563
Biological Process	GO:0048659	smooth muscle cell proliferation	IMP	J:172144
Biological Process	GO:0048659	smooth muscle cell proliferation	ISO	J:164563
Biological Process	GO:0044342	type B pancreatic cell proliferation	IDA	J:202162